Bayanin PRL-8-53
Talla ta PRL-8-53 a matsayin magungunan ƙwayoyin cuta wanda aka gano a farkon shekarun 1970. Nikolaus Hansl, farfesa a jami'ar Creighton, kwatsam ya gano nootropic yayin aiki akan aminoethyl meta benzoic acid esters.
Tun lokacin da aka kafa ta, wannan ƙarin ya gudana cikin takaddama da kuma gwajin ɗan adam. Binciken asibiti shine babbar hujja cewa PRL-8-53 don karatu yana inganta ƙwaƙwalwar ajiyar gajeren lokaci da kuma iya magana.
PRL-8-53 ba ta karɓi amincewar FDA ba, amma ƙari ne wanda ba a tsara shi ba a Amurka. Kuna iya siyan PRL-8-53 kyauta kyauta azaman babban kantin sayar da kanti.
Menene PRL-8-53?
PRL-8-53 ya samo asali ne daga benzoic acid da benzylamine. A kimiyance, an san shi da suna 3- (2- (benzyl (methyl) amino) ethyl) benzoate.
Tun daga ƙarshen 1970s, PRL-8-53 ya kasance duk fushin azaman magani na psychoactive don haɓaka ayyukan kwakwalwa. Aƙalla, akwai gwajin ɗan adam wanda ya ci nasara wanda ke tallafawa ingancinsa. Bayan haka, nazarin PRL-8-53 a kan Reddit yana tallafawa ingancin wannan ƙarin don inganta ƙwaƙwalwar ajiya da ilmantarwa.
Farfesa Hansl asali ya gano hakan PRL-8-53 nootropic yana haɓaka ƙwaƙwalwar ajiyar ƙwaƙwalwa da ambaton magana. Koyaya, magungunan kuma yana magance baƙin ciki, damuwa, damuwa, da gajiya.
Ayyukan PRL-8-53
Saboda rashin isassun karatun bincike akan PRL-8-53, ainihin yadda ake gudanar da ayyukanta wani abu ne mai wuyar fahimta. Koyaya, masana kimiyya sunyi tsammanin kwayar tana haɓaka ayyukan kwakwalwa ta hanyoyi uku.
Saukewa: PRL-8-53 yana kunna ɓoyewar acetylcholine, wanda shine babban ɗan kwaya, wanda ke da alhakin aiki ƙwaƙwalwa da ilmantarwa.
Wannan magungunan ƙwayoyin cuta yana aiki akan tsarin dopaminergic ta hanyar daidaita matakan dopamine lafiya. Menene ƙari, shan Rashin ciki na PRL-8-53 magani zai hana yawan kwayar serotonin. Wannan tasirin ya ɗora matakan damuwa don gudanar da juyayi, sauyin yanayi, da rashin bacci.
Fa'idodin PRL-8-53
Yana kara karfin Koyi
PRL-8-53 foda yana tabbatar da haɓaka haɓaka da ikon koyo. Supplementarin yana haifar da tuna bayanai, kalmomi, da ra'ayoyi daban-daban. Sabili da haka, ya zama magungunan ƙwaƙƙwaran karatu tsakanin ɗaliban da ke son tafiya ta cikin gwaji mai wuya.
PRL-8-53 don karatu na iya inganta haɓaka, musamman yayin ƙoƙarin fahimtar sabbin abubuwa. Wasu masu tabin hankali suna da'awar cewa shan wannan ƙwaya mai kaifin ƙwaƙwalwa yana kiyaye ka, kuma ƙila za ka wahala yayin bayyana sabbin kayan aiki. Waɗannan fa'idodin na PRL-8-53 na iya zama sabon wayewar gari ga masu ƙwaƙwalwa waɗanda ke ɗagewa don wasu ƙididdigar kimiyyar lissafi da yawa ko gwajin baki na rashin ƙarfi.
Inganta Memory
Ofaya daga cikin mahimman tasirin PRL-8-53 ya haɗa da haɓaka ƙwaƙwalwa. Nootropic yana kunna acetylcholine da tsarin dopaminergic, waɗanda suke da mahimmanci don cognition.
A cikin gwaji na asibiti wanda ya shafi batutuwan kiwon lafiya 47, farfesa Hansl ya lura cewa waɗanda suka ɗauki PRL-8-53 sun fi kyau a gwajin tunowa fiye da mahalarta kan placebo. Bayan wannan, wannan ƙwaƙwalwar na iya ɗaukar kusan mako guda.
Kafin yin gwaji tare da batutuwa na mutane, Hansl ya lura cewa PRL-8-53 yana amfani da tasirin ƙwaƙwalwar bera. Arin ya sanya samfurin murine don tunawa da haɗakar da martani ga halin damuwa.
Inganta Motsa jiki da Rage gajiya
PRL-8-53 miyagun ƙwayoyi na baƙin ciki yana nuna abubuwan haɓaka na dopaminergic. Haɗin yana haɓaka aikin dopamine, sinadarin kwakwalwa wanda ke shafar motsawa, haɓaka yanayi, da rage gajiya. Sabili da haka, yana haɓaka lafiyar halayyar mutum, tare da yiwuwar magance rikicewar hankali kamar ADHD da schizophrenia.
Duk da fa'idodi masu kyau na PRL-8-53, bai kamata ka yi amfani da nootropic azaman yanki don maganin likitan ka ba. Wannan mahaɗan ba'a nufin shi don dalilai na jinya ko maganin cututtuka.
Yadda za'a ɗauki PRL-8-53?
The hankula Sashi na PRL-8-53 yana kusan 5mg kowace rana, ana ɗauka azaman ƙarin maganin baka. Kodayake akwai iyakantaccen bincike don kafa mafi kyawun zangon gwaji, gwajin ɗan adam na farko ya yi amfani da 5mg. Saukewa ta hanyar wasu bayanan PRL-8-53 ya tabbatar da cewa wasu masu amfani masu amfani suna ɗaukar kamar 10mg zuwa 20mg na ƙarin.
Idan kuna gudanar da ƙarin don ƙirƙirar ƙwaƙwalwar ajere na ɗan gajeren lokaci, kamar lokacin ɗaukar gwaji, tabbatar da amfani dashi sa'o'i biyu kafin ainihin aikin.
PRL-8-53 nootropic is available in powder, pill, and liquid forms. You can choose to swallow the tablet or add it to your drink; whichever is convenient for you. Although you can opt for sublingual administration, this method may be numbing to your tongue. Most users would prefer taking PRL-8-53 orally.
Tari na PRL-8-53
A halin yanzu, babu ingantaccen shawarwarin tari na PRL-8-53. Ba'a san yiwuwar hulɗar wannan mahaɗin tare da wasu magungunan ƙwayoyi masu ruɗu ba. Bayan haka, PRL-8-53 yana da ƙarfi sosai, don haka, ba lallai ba ne a haɗa shi tare da wasu ƙwayoyin cuta masu haɓaka ƙwaƙwalwa.
Ba mu ba da shawara ko ba da shawarar kowane Tari na PRL-8-53. At least, it would be best if you do not dare it with magunguna masu kyau having similar effects. Despite this stern warning, some users within the psychonautic community confess that stacking PRL-8-53 powder with Alpha-GPC, piracetam, IDRA-21, and theanine gives them maximum therapeutic benefits.
Shin akwai wasu sakamako masu illa na PRL-8-53?
So far, there are no recorded PRL-8-53 illa. The only available resources date back to 1970s during the clinical and preclinical trials of the nootropic. In the human study, the participants exhibited no adverse symptoms on a dose of 5mg per day.
Although there are no clinical PRL-8-53 illa on record, make sure to maintain low doses. According to the rat study, high amounts of this supplement impairs movement.
Masu amfani da Kwarewa
Akwai kwarewar mai amfani da yawa akan Reddit da kantin Amazon game da tasirin Damuwa na PRL-8-53 nootropic.
Duba wasu daga cikin bayanan PRL-8-53;
Ilmantarwa da Memory kyautata
Chrico031 yana cewa;
“Ina amfani da PRL-8-53 sosai a duk lokacin da nake da laccoci don haddacewa. Yana da matukar banbanci kan yadda zan iya haddace abu da sauri. ”
Inmy325xi yana cewa;
“Na lura da karin magana da PRL da kaina. Haɗe tare da maganin kafeyin, kayan aikin karatu ne mai kyau. ”
Tsarin PRL-8-53
Baliflipper yana cewa;
“Na fara da kananan allurai kuma na yi aiki har na kai ga yawa. Tabbas na ji cewa 10mg babban maganin yau da kullun ne… Duk da haka, na yanke shawarar gwada 20mg a ranar Juma'a don gwajin Neuroscience na kuma yi mamakin haɓakawa a cikin tuno… Na ji cewa mafi girman allurai ba shakka sun taimaka wajen tuna kuma ya kasance babban taimako ga gwaje-gwaje . ”
PRL-8-53 Matsayi
Lifehole yana cewa;
"Ina ɗauka da safe lokacin da na farka (11 na safe) tare da Noopept, L-theanine, bupropion, vortioxetine, da tianeptine really Ba shi yiwuwa a gane abin da ake yi da irin wannan tarin ƙwayoyi dangane da biranen gari ed"
Chrico031 yana cewa;
“A yanzu haka ina yin IDRA-21 da PRL-8-53 kowace rana. Ina son haduwa, kuma hakan yana sa haddacewa da fahimtar sabbin abubuwa ya fi sauki. ”
PRL-8-53 Ku ɗanɗani
Baliflipper yana cewa;
“Kamar yawancin masu amfani da yare, yana da ɗanɗano mara kyau. Duk da haka, ba shi da kyau kamar Noopept… hakan kuma zai sa harshenka ya lalace a farkon lokutan… Abubuwan fa'idar sun fi ƙarfin dandano.
Sakamakon PRL-8-53
Omniavocado yana cewa;
“Na sami ɗan ƙwaƙwalwar da ta fi ƙarfin rauni bayan tasirin ya lalace ko da da ƙananan ƙwayoyi. Bayan an sha kashi na karshe, sai na ji ba dadi, dan ba dadi. ”
Mai amfani da ba a sani ba yana cewa;
"A kan allurai sama da 30mg a baki da kuma 15mg a bayyane, na sami ciwon kai da kuma wani sakamako mai ban mamaki dangane da hangen nesa na."
Kammalawa
PRL-8-53 powder is a promising nootropic that remains unexplored in the scientific realm. The only tangible evidence of its effectiveness is as old as five decades. However, enthusiastic neurohackers are banking on it as a potent memory enhancer with minimal PRL-8-53 illa.
Arin ƙarin shine manufa don ƙwaƙwalwar ajiyar ɗan gajeren lokaci. Bayanin da aka tattara daga ƙwararrun masu amfani da binciken binciken da aka samo ya tabbatar da hakan Damuwa na PRL-8-53 magani zai inganta ƙwaƙwalwar ajiya har zuwa 200%.
Halin wannan nootropic tare da wasu magunguna har yanzu abu ne mai ban mamaki. Saboda haka, ba a san amincinsa da haƙƙinsa ba. Don haka, gwada tarin PRL-8-53 ba zaɓi bane ko dai. Tuntuɓi likitanka kafin shan PRL-8-53 tare da wasu magungunan ƙwayoyi.
Kuna iya siyan PRL-8-53 a foda ko nau'in kwaya azaman Ƙari na nootropic.
References
- Hansl, NR, & Mead, BT (1978). PRL-8-53: Ingantaccen ilmantarwa da riƙewa a cikin mutane sakamakon ƙarancin maganin ƙwayoyin cuta na sabon wakili na psychotropic. Psychopharmacology (Berl).
- Hansl, NR (1974). Wani sabon labari mai suna spasmolytic da wakilin CNS masu aiki: 3- (2-benzylmethylamino ethyl) benzoic acid methyl ester hydrochloride.
- McGaugh, JL, & Petrinovich, LF (1965). Hanyoyin kwayoyi akan ilmantarwa da ƙwaƙwalwa. Binciken Duniya na Neurobiology.
- Kornetsky, C., Williams, JE, & Bird, M. (1990). Hankali da motsawar tasirin magungunan ƙwayoyi. NIDA kundin bincike.
- Giurgea, C. (1972). Ilimin kimiyyar hada magunguna na kwakwalwa. Oƙari a cikin tunanin nootropic a cikin psychopharmacology. Ainihin Pharmacol (Paris).
- Hindmarch, I. (1980). Ayyukan Psychomotor da magungunan psychoactive. Jaridar British Journal of Clinical Pharmacology.
- RAW PRL-8-53 MARA (51352-87-5)