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N-Acetyl-L-cysteine ​​ethyl ester (NACET) (59587-09-6)

NACET (N-Acetylcysteine ​​ethyl ester) wani sabon abu ne wanda yake da asali wanda ya dace da tsarin cysteine ​​mai ƙwaƙwalwar ƙwayar cuta tare da sifar likitancin da baƙon abu ba…


Status: A Mass Production
Naúra: 25kg / Drum

description

NACET (59587-09-6) Bayani

Product Name NACET (59587-09-6)
Chemical Name R) -ethyl 2-acetamido-3-mercaptopropanoate;
L-Cysteine, N-acetyl-, etyl ester;
N-ACETYL-L-CYSTEINE ETHYL ESTER;
ethyl (2R) -2-acetamido-3-sulfanylpropanoate;
L-Cysteine, N-acetyl-, etyl ester;
N-Acetylcysteine ​​ethylester;
CAS Number 59587-09-6
InChIKey MSMRAGNKRYVTCX-LURJTMIESA-N
Smile CCOC (= O) C (CS) NC (= O) C
kwayoyin Formula C7H13NO3S
kwayoyin Weight 191.25
Monoisotopic Mass 191.061614 g / mol
Ƙaddamarwa Point 44.1-44.5 ° C
tafasar Point 337.6 ± 32.0 ° C (Tsinkaya)
yawa 1.138 ± 0.06 g / cm3 (Tsinkaya)
Launi Kusa da fari
Aikace-aikace Nootropics da ƙwaƙwalwar ƙwaƙwalwa, ana iya amfani dasu don haɓaka ƙwaƙwalwa, mayar da hankali, kerawa, hankali da motsawa. Hakanan za'a iya amfani dashi azaman karin abinci.

Mene ne NACET(N-Acetylcysteine ​​ethyl ester)?

NACET (N-Acetylcysteine ​​ethyl ester) wani abu ne wanda aka samo asali na lipophilic cell-permeable cysteine ​​cysteine ​​tare da wani sabon nau'in sikandire na likitancin magani da kuma kyamar maganin antioxidant. NACET yana da bioavailability mai tsayi na baki. Dogaro ne mai mahimmanci na antioxidant kuma mai wadatarwa na GSH, wanda ke da alaƙa da sinadarin acid na N-acetyl -L ya bambanta da -cysteine ​​(NAC). NACET farin farar foda ne a zazzabi a daki kuma yana narkewa cikin ruwa da sinadarai.

NAC asali ne na cysteine. Tun daga shekarun 1970, ana amfani da shi don kula da marasa lafiya tare da maganin hana ƙwayoyin cuta na acetaminophen da raunin jijiyoyin jiki, kuma ana tallata shi azaman magani da ƙari na abinci. Idan aka kwatanta da NAC, NACET yana da mafi yawan lipophilicity da ingantattun kayan magunguna. Yana da damar maye gurbin NAC na pharmacological, a matsayin wakili na mucolytic, antioxidant, mai ba da kyautar GSH, paracetamol antidote, kuma aƙalla Donor na mai ba da jijiyoyin H 2 S da wakilin kariya na UV.

Kari akan haka, an tabbatar da karfin nucleophilicity da rage karfin NACET a cikin kwayoyin halittar jini na mutum. An samo shi don tarawa cikin sel jini na mutum, yana tsayayya da lalacewa ta hanyar lalacewa ta hanyar hydroperoxides. Saboda haka, yuwuwar NACET a matsayin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ta ƙasa mafi girma fiye da ta NAC methemoglobinemia da sauran abubuwa masu ƙarfi. Nazarin cikin berayen sun gano cewa NACET yana da sauri sosai fiye da NAC yayin da ake sarrafa NACET ta baka. Zai iya shiga cikin sel kuma ya samar da NAC da cysteine, wanda ke haɓaka hydrogen sulfide (H (2) S) a cikin kewaya. Kyakkyawan ɗan takara ne don yin amfani da baka a matsayin mai samar da H (2),

Fa'idodin NACET (N-Acetylcysteine ​​ethyl ester)

A matsayin mai amfani da maganin antioxidant, NACET yana da fa'idodi masu yawa akan lafiyar ɗan adam.

- Inganta yanayin kiwon lafiya da yawa da sauƙaƙa alamun bayyanar cututtuka;

- Jiyya na acetaminophen overdoses, kariya daga kodan da hanta.

- Yana haɓaka aikin huhu ta rage kumburi da rurrushe gamsai, hakan zai rage cututtukan da ke damun mutum.

- Inganta lafiyar kwakwalwa ta hanyar sarrafa glutamate da haɓaka glutathione, za'a iya amfani dashi don magance cututtuka irin su cutar Alzheimer da cutar Parkinson;

- Inganta haihuwa a cikin maza da mata

- Zai iya inganta aikin rigakafi a cikin cututtukan da yawa, hana lalacewar iskar shaka a zuciya, da rage haɗarin cututtukan zuciya.

- Zan iya tsayar da Jinin Ruwa ta rage Rage kumburi a Kwayoyin Fat

Kayan aikin NAECT (N-Acetylcysteine ​​ethyl ester)

Saboda NACET ya nuna sakamako mai yawa akan cutar kwakwalwa, cututtukan numfashi da cutar kwakwalwa, ana amfani dashi azaman magani da kuma karin abinci don kare kwakwalwa, haɓaka aikin kwakwalwa da na jiki, don inganta ƙwaƙwalwar ajiya, ƙwarewa da wasan motsa jiki.

reference:

  • Giustarini D, Milzani A, Dalle-Donne I, Tsikas D, Rossi R. N-Acetylcysteine ​​ethyl ester (NACET): wani abu mai ma'ana na cysteine ​​cell-permeable cysteine ​​wanda aka saba dashi tare da sifofin magunguna na yau da kullun wanda ba a san shi ba da kuma damar da ta shahara. Pharmacol na Biochem. 2012 Dec 1; 84 (11): 1522-33. doi: 10.1016 / j.bcp.2012.09.010. Epub 2012 Sep 20. PMID: 23000913.
  • S-Nitroso-N-acetyl-L-cysteine ​​ethyl ester (SNACET) da kuma N-acetyl-L-cysteine ​​ethyl ester (NACET) -Cisanin magungunan masu amfani da magunguna tare da bayanan bayanan magunguna na musamman don amfani da baki kamar KO, H2S da masu siyarwar GSH da azaman antioxidants: Sakamako da dubawa. 2018 Feb; 8 (1): 1-9. doi: 10.1016 / j.jpha.2017.12.003. Epub 2017 Dec 13. Bita. PMID: 29568662
  • N-acetylcysteine ​​ethyl ester a matsayin GSH mai haɓakawa a cikin ƙwayoyin endothelial na ɗan adam: Nazarin kwatancen tare da wasu kwayoyi. 2018 Oct; 126: 202-209. doi: 10.1016 / j.freeradbiomed.2018.08.013. Epub 2018 Aug 14. PMID: 30114478.
  • DimitriosTsikasa, Kathrin S.Schwedhelma, Andrzej Surdackib, Daniela Giustarinic, Ranieri Rossid, Lea Kukoc-Modune, George Kediaf, Stefan Ückertf. S-Nitroso-N-acetyl-L-cysteine ​​ethyl ester (SNACET) da kuma N-acetyl-L-cysteine ​​ethyl ester (NACET) –Wannan yan takarar magungunan likitanci tare da bayanan bayanan magunguna na musamman don amfani da baki kamar KO, H2S da GSH masu sayarwa da azaman antioxidants: Sakamako da dubawa. Jaridar Nazarin Magunguna. Juz'i na 8, fitowa ta 1, Fabrairu 2018, Shafuka 1-9.

BATSA DA TATTAUNAWA:

Ana Samun Wannan Abubuwan ne Don Amfani da Bincike Kawai. Sharuɗɗan Siyarwa suna Aiwatarwa. Ba don Amfani da Dan Adam bane, ko Likita, dabbobi, ko Amfani na Gida.


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