Chenodeoxycholic Acid (CDCA) Foda

Janairu 12, 2022

Chenodeoxycholic acid foda yana ɗaya daga cikin manyan bile acid da aka haɗa daga cholesterol a cikin hanta na mutane da dabbobi. Ana iya amfani dashi don magance gallstones da xanthoma na cerebral tendon.


Status: A Mass Production
Naúra: 25kg / Drum
Capacity: 1100kg / watan

 

Bayanan Bayani na Chenodeoxycholic Acid

Product Name Chenodeoxycholic acid
Chemical Name (R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
Synonym Chenodeoxycholic acid;

Anthropodeoxycholic acid;

Anthropodesoxycholic acid;

CCRIS 2195;

Chendol;

chenic acid;

Chenix;

Chenodeoxycholic acid;

Chenodesoxycholic acid;

Chenodiol;

Gallodesoxycholic acid;

NSC 657949;

Xenbilox

CAS Number 474-25-9
InChIKey RUDATBOHQWOJDD-BSWAIDMHSA-N
kwayoyin FƘararraki C24H40O4
kwayoyin Wtakwas 392.57
Monoisotopic Mass 392.29265975
Ƙaddamarwa Point 165-167 ° C (lit.)
Tafasa Point  437.26 ° C (m kimantawa)
yawa 0.9985 (ƙananan ƙididdiga)
Launi White zuwa kashe-farin
solubility  BABU RASHIN HANKALI
Storage Taikin zafi  dakin temp
Aikace-aikace An yi amfani da Chenodeoxycholic acid a cikin binciken don tantance tasirin sa azaman maganin maye gurbin na dogon lokaci don cerebrotendinous xanthomatosis (CTX). Hakanan an yi amfani da shi a cikin binciken don bincika tasirinsa akan ƙananan ƙwayar hanji na bile acid a cikin marasa lafiya tare da ileostomy.
Rahoton Gwaji Ya Rasu

 

Chenodeoxycholic Acid

Chenodeoxycholic acid, wanda aka fi sani da chenodiol, wani nau'in bile acid ne wanda aka samo shi ta dabi'a a cikin jikin mutum kuma ana amfani dashi a waje don amfanin chenodeoxycholic acid. Ana ba da shawarar yin amfani da wannan bile acid don kula da yanayin kiwon lafiya daban-daban kuma waɗannan shawarwarin suna goyan bayan shaidar kimiyya. An yi nazarin tsarin aikin chenodeoxycholic acid daki-daki, a cikin bincike daban-daban, tare da manufar gano amfani, fa'idodi, da illa na chenodiol.

 

Menene Bile Acids?

Bile acids sune, kamar yadda sunan ya bayyana da kyau, sinadarai na steroidal da ake samu a cikin bile na ɗan adam da bile na sauran dabbobi masu shayarwa. Bile shi ne ruwan narkewar abinci wanda hanta ke hadawa da adanawa a cikin gallbladder. Yawancin bile acid suna haɗe a cikin hanta kuma suna iya haɗuwa da amino acid; taurine da glycine, don samar da bile salts.

Bile acid ɗin da hanta ke haɗawa ana kiran su azaman bile acid na farko kuma sun haɗa da colic acid da chenodeoxycholic acid. Kafin ɓoye waɗannan sinadarai na farko na bile acid, ana canza su zuwa gishirin bile. Wadannan gishirin bile ne ake sakin su, su kai ga kananan hanji. Da zarar a cikin duodenal sashin ƙananan hanji, ana cire amino acid ɗin da ke hade da bile acid ta hanyar flora na hanji. Suna fuskantar ƙarin gyare-gyare wanda ke haifar da colic acid da aka canza zuwa deoxycholic acid da chenodeoxycholic acid zuwa lithocholic acid. Deoxycholic da lithocholic acid sune bile acid na biyu.

Tun da bile acid an haɗa su a cikin hanta daga cholesterol, suna da tsarin zobe na steroid a matsayin tushe. Wannan shine daya daga cikin dalilan da yasa bile acid ke aiki kamar hormones na steroid a cikin jiki kuma suna yin muhimmiyar rawa wajen watsa sigina. Duk da haka, babban aikin bile acid shine inganta narkewar mai da mai da ake cinyewa, kuma suna yin haka ta hanyar kewaye da mai abinci, haifar da micele.

Ana yin Micelle lokacin da aka shafe lipids a cikin abinci kuma ana ɗaukar su a cikin wani yanki da aka yi da gishirin bile. Yana da kyau a ambata cewa micelles sun ƙunshi bile acid amma an samo su ta hanyar bile salts waɗanda ke kwance a kan ruwa da haɗin lipid. Wurin su tare da yanayin hydroponic da hydrophilic suna ba da damar gishirin bile don samar da waɗannan miceles a daidaitaccen taro. Yana da mahimmanci a lura cewa samuwar micelle shine mabuɗin don rushewar kitse ta hanyar da ake bukata enzymes.

Bile acid kuma yana da wasu mahimman ayyuka, ɗaya daga cikinsu shine rage flora na hanji, wanda kuma yana da mahimmanci ga samuwar bile acid na biyu. Cire cholesterol da sauƙaƙe shayar da Bitamin masu narkewar mai wasu ne daga cikin sauran ayyukan bile acid. Suna taka muhimmiyar rawa a cikin jikin mutum kuma wani abu mai ƙanƙanta a matsayin canjin maida hankali zai iya canza ilimin lissafin jiki sosai.

 

Menene Chenodeoxycholic Acid (CDCA) Foda?

Chenodeoxycholic acid foda (474-25-9) ko Chenodiol Foda wani abu ne na bile acid wanda zai iya.

a cinye don cimma fa'idodi iri ɗaya kamar waɗanda aka samu daga chendiol na endogenous. Ana amfani da foda ta hanyar warkewa, da farko don maganin gallstones, wanda kawai adibas na bile mai taurin gaske a cikin gallbladder. Hakanan za'a iya amfani da Chenodiol don magance wasu cututtuka kamar al'amurran da suka shafi haɗin bile da metabolism. Yana da wani magani da aka yarda da FDA wanda aka saba wajabta don cututtukan hanta wanda, a ainihin su, ya taso daga al'amurran da suka shafi bile.

 

Daga ina Chenodeoxycholic acid foda ya fito?

Ana samar da chenodeoxycholic acid ta ƙwayoyin hanta daga cholesterol. Exogenous chenodiol foda duk da haka an keɓe shi daga bile na swan, Cygnus melanocoryphus.

 

Ta yaya Chenodeoxycholic Acid Foda ke Aiki?

Chenodioxycholic acid foda ana amfani dashi da farko don maganin gallstones, wanda ya kasu kashi biyu bisa ga abin da ke ciki da kuma bayyanar su akan rediyo. Chenodiol kawai yana da ikon magance gallstones da suka ƙunshi cholesterol kuma suna bayyana radiolucent. Gallstones da suke radiopaque ko kuma idan sun kasance radiolucent amma sun hada da bile pigment, CDCA foda ba a kula da su.

Chenodiol yana maganin gallstones ta hanyar narkar da cholesterol a cikin su wanda shine sakamakon lalata cholesterol na biliary ta CDCA foda. Tsarin chenodeoxycholic acid foda na aiki yana da sauƙi, kamar yadda ya hana kira na cholesterol da colic acid a cikin hanta. Bayan lokaci, yana maye gurbin cholic acid da abubuwan da suka samo asali a cikin jiki. Jikewar cholesterol saboda haka yana raguwa, yana tilasta duwatsun cholesterol su narke don daidaita taro cholesterol.

Lokacin da aka sha da baki, chenodiol yana kan hanyarsa zuwa hanji, inda aka tsoma shi kuma a aika shi zuwa hanta don haɗuwa da taurine da glycine. Da zarar an haɗa su, ma'ana an haɗa gishirin bile, CDCA bile salts ana fitar da su cikin bile. CDCA bile salts sun kasance a cikin wurare dabam dabam na enterohepatic ma'ana cewa matakan jini ko matakan fitsari na CDCA za su kasance da canji sosai.

 

Menene Chenodeoxycholic Acid Ake Amfani dashi Don?

Ana amfani da Chenodeoxycolic acid foda don:

  • Maganin gallstones na radiolucent cholesterol, ba za a iya yin aiki da su ba saboda kasancewar wasu yanayi waɗanda ke sa tiyata ya zama zaɓi mai wahala.
  • Jiyya na cerebrotendineous xanthomatosis
  • Inganta aikin hanji da sarrafa maƙarƙashiya
  • Maganin kurakurai masu ciki ko bishiyar biliary
  • Gudanar da hyperlipidemia

 

Menene Muhimmancin Chenodeoxycholic Acid A Cikin Narkewa?

Chenodeoxycholic acid yana da fa'ida musamman wajen sauƙaƙe narkewar lipid ta hanyar samar da micelle a kusa da fatty acid ɗin da aka sha daga hanji. Manufar kafa micele a kusa da lipids shine a sanya su mai narkewar ruwa ta yadda za'a iya kawo su saman hanji don mafi kyawun sha. Micelles suna samuwa ne ta hanyar gishirin bile kuma suna dauke da acid bile kamar su chenodeoxycholic acids, don haka, yin na karshen ya zama muhimmin sinadari don sauƙaƙe narkewar lipid a jikin mutum.

 

Abin da Fa'idodi & Tasirin Chenodeoxycholic Acid Foda?

Chenodeoxycholic acid foda an yarda da FDA don amfani da shi a cikin kula da gallstones da wasu cututtuka. Akwai 'yan fa'idodin chenodiol waɗanda masu amfani suka ruwaito kuma an tabbatar da su ta ingantaccen bayanan kimiyya. Ya kamata a yi la'akari da waɗannan fa'idodin lokacin da ake rubuta CDCA foda don tabbatar da cewa amfanin ya fi girma da haɗari.

Gudanar da gallstones shine babban aikin Chenodiol, duk da haka, yana sarrafawa da kuma magance takamaiman nau'in gallstone. Idan gallstone ba radiolucent ba kuma ya ƙunshi cholesterol, yin amfani da CDCA foda ba zai isa ya rushe ba. Wani binciken da aka yi tare da manufar kwatanta zaɓuɓɓukan magani daban-daban na gallstones na cholesterol ya gano amfani da chenodiol tare da lithotripsy don zama maganin zabi. Ana ba da shawarar Chenodiol musamman lokacin da fiɗa daga gallbladder ba abu ne mai yiwuwa ba.

Chenodeoxycholic acid foda amfanin kuma ya hada da maganin cututtuka na rayuwa irin su xanthomas cerebrotendinous. Wannan cuta ta haɗa da maye gurbi a cikin kwayar halitta wanda ke ɓoye enzyme da ake buƙata don canza cholesterol zuwa bile acid a cikin hanta. Rashin wannan enzyme yana haifar da raguwar raguwa a cikin haɗin bile acid da kuma karuwa mai yawa a cikin cholesterol wanda ke taruwa a yankuna daban-daban na jiki, don haka, haifar da xanthomas. Yin magani tare da exogenous bile acid kamar chenodiol yana taimakawa rage yawan ƙwayar cholesterol a cikin jiki kuma yana inganta alamun wannan cuta ta kwayoyin halitta.

Chenodeoxycholic acid, tare da epimer, ursodeoxycholic acid, an yi imani da cewa suna da antioxidant da anti-inflammatory Properties, ko da yake waɗannan amfanin an fi ganin su tare da ursodiol. Chenodiol kuma yana da amfani a cikin maganin kurakuran da aka haifa na metabolism da sauran cututtukan hanta mai tsanani.

 

Yadda ake shan Chenodeoxycholic Acid Foda?

(1) Kafin shan chenodiol foda

Kafin fara shan chenodeoxycholic foda, an bada shawarar sosai don sanar da likitan likitancin duk magunguna na yanzu da na baya da kuma yanayin kiwon lafiya don tabbatar da cewa babu yiwuwar hulɗar da zai iya haifar da sakamako mai mutuwa. Alal misali, CDCA foda yana da sakamako masu illa masu yawa waɗanda ke da alaƙa kai tsaye ga aikin hanta wanda shine dalilin da ya sa yin amfani da shi a cikin cututtukan hanta ya hana. Hakanan yana da mahimmanci don sanar da likita game da duk wani rashin lafiyar abin da ke cikin kwamfutar hannu na chendiol ko foda, don tabbatar da rage haɗarin sakamako masu illa.

 

(2)Chenodeoxycholic acid foda sashi

Chenodiol foda ya kamata a sha da baki, ko dai tare da abinci ko ba tare da shi ba. Madaidaicin ƙwayar chenodeoxycholic acid foda yana dogara ne akan nauyin mutum, yanayin kiwon lafiya da ake amfani da shi, da kuma mayar da martani ga farfadowa. Abin da sashi na ƙarshe ke nufi shi ne cewa kashi na farko da kuma kula da kashi na chenodeoxycholic acid foda na iya bambanta sosai dangane da yadda jiki ya dace da shi. Gabaɗaya, ga babba, adadin shine tsakanin 13 MG da 16 MG kowace kilogram na nauyi.

Ana amfani da foda na Chenodiol da farko don maganin gallstones, kuma yayin da zasu iya ɗaukar lokaci mai tsawo don cikakkiyar lalacewa da kuma cirewa, ana iya amfani da foda har zuwa shekaru biyu. Koyaya, bayan shekaru 2, yakamata a daina amfani da chenodeoxycholic acid saboda bile acid yana da tasirin sakamako masu illa na hanta. Bugu da ƙari, alamun alamun gallstones ko wasu cututtuka na biliary na iya ɗaukar har zuwa shekara guda don ɓacewa tare da CDCA foda amfani.

 

(3)Me zai faru idan na rasa kashi or wuce gona da iri?

Idan an rasa kashi na chenodiol foda, yana da kyau a bar wannan zama kuma ku ɗauki kashi na gaba a lokacin da aka saba. Yin amfani da allurai sau biyu na iya haifar da wuce gona da iri kuma ba a ba da shawarar ba. Duk da yake babu da yawa da aka ruwaito overdoses tare da chenodiol foda, akwai 'yan da ke ba da garantin gargadi. Idan ana sa ran yin amfani da fiye da kima kuma wanda abin ya shafa yana da wahalar numfashi, ya kamata a nemi taimakon likita nan da nan.

 

(4)Menene zan guje wa yayin shan chenodiol?

Yin amfani da foda na chenodeoxycholic acid an hana shi a wasu yanayi, kamar:

  • hepatitis
  • Cirrhosis
  • Cutar cutar
  • Cutar cututtuka
  • Toshewa a cikin hanji
  • Hemolytic anemia ko wasu cututtuka ko hemolysis
  • Amfani da Alcohol akai-akai
  • Shaye-shaye
  • Pregnancy

Yin amfani da chenodiol a lokacin daukar ciki na iya zama mai tsanani teratogenic ga tayin kuma yana da cikakken contraindicated. A lokacin shayarwa, duk da haka, ba a sani ba idan CDCA na bile acid ya shiga cikin nono kuma saboda haka, yana da ɗan ƙima. Shawarar likita kafin fara shan chenodeoxycholic acid foda yayin da ake shayar da nono sosai.

 

Wadanne Magunguna Zasu Yi hulɗa da Chenodeoxycholic Acid?

Abubuwan da aka ruwaito na chenodeoxycholic acid sun fi dacewa saboda tasirin bile acid kai tsaye, kuma da wuya saboda hulɗar foda tare da wasu magunguna. Wannan ba, duk da haka, yana nufin cewa chenodeoxycholic acid foda ba zai yi hulɗa tare da wasu magunguna ba. Idan an dauki chenodiol tare da takamaiman kayan ganyayyaki ko magunguna, tasirin foda zai canza sosai. Haɗarin haɓaka mummunan tasiri kuma zai ƙaru tare da waɗannan hulɗar.

Musamman magunguna waɗanda ba su da ikon yin hulɗa tare da chenodeoxycholic acid foda sune:

  • Cholestyramine
  • kolestipol
  • Magungunan hana haihuwa ko maganin maye gurbin hormone
  • Antacids masu dauke da aluminium a matsayin manyan sinadaran su kamar Almacone, Gelusil, Maalox, Mag-al Plus, Mylanta, Rulox, da sauransu.
  • Magungunan jini kamar warfarin, Coumadin, Jantoven.

Cholestyramine da colestipol duka biyun bile acid sequestrants ne waɗanda ke aiki a cikin ciki ta hanyar kama bile acid, saboda haka, yana hana aikin su. Shan bile acid sequestrants tare da bile acid zai sa na karshen ya yi yawa kuma ba za a ga wani fa'ida ba. Maimakon haka, yanayin likita wanda aka rubuta chenodeoxycholic acid zai yi muni.

Yana da mahimmanci kada ku ɗauki chenodiol tare da wasu nau'ikan bile acid saboda hakan na iya ƙara haɗarin sakamako masu illa. Ana ba da shawarar sosai a tuntuɓi likita a sanar da su duk wasu bitamin ko magungunan da mutum zai iya sha, kafin a fara chenodiol saboda wasu magunguna na iya buƙatar dakatar da su kafin fara chenodeoxycholic acid. Ba wai kawai ba, ambaton magungunan da aka yi amfani da su kwanan nan sannan kuma an dakatar da su na iya zama da amfani kamar yadda wasu kwayoyi zasu iya zama a cikin tsarin na dogon lokaci.

 

Menene Bambanci Tsakanin Ursodeoxycholic Acid Foda Da Chenodeoxycholic Acid Foda?

Chenodeoxycholic acid foda da Ursodeoxycholic acid foda ne biyu daga cikin manyan exogenous bile acid da aka wajabta da kuma amfani da gudanar da gallstones.

 

Ursodeoxycholic acid foda

Ursodeoxycholic acid foda ko ursodiol shine acid bile na biyu a cikin jikin mutum, wanda aka haɗa shi daga gyare-gyaren bile salts ta flora gut. Ba kamar chenodeoxycholic acid wanda shine farkon bile acid kuma ya haɗa a cikin hanta, ursodiol yana haɗawa a cikin ƙananan hanji. An samar da foda na ursodeoxycholic acid mai waje daga cholic acid wanda aka fitar daga bile na bovine.

 

Kwatanta fa'idodi da aiki

Ana amfani da Ursodiol da Chenodiol don rushewar gallstone, duk da haka, sauran amfanin biyun ba su da kama. Hakanan ana amfani da Ursodiol don kula da biliary cholangitis na farko da sclerosing cholangitis na farko. Saboda mafi girman bayanin martabarsa, ursodiol shine zaɓin bile acid don maganin cholestasis na ciki.

 

Manyan Bambance-bambance

Babban bambanci tsakanin chenodeoxycholic acid foda da ursodeoxycholic acid foda shine cewa karshen ba hepatotoxic ba ne kuma ana iya amfani dashi da yardar kaina yayin da tsohon shine hepatotoxic kuma zai iya haifar da cutar hanta mai haɗari. Chenodiol shine farkon bile acid kuma Ursodiol shine bile acid na biyu tare da kasancewa epimer na chenodiol.

Nazarin kwanan nan da aka yi tare da manufar kwatanta ursodiol da chenodiol sun gano cewa UDCA ta fi tasiri wajen rage girman gallstones a alamar watanni 3 da alamar watanni 6. Duk da haka, bayan watanni 12 da ingancin duka biyu na chenodiol da ursodiol sun daidaita kuma babu wani bambance-bambance mai mahimmanci tsakanin su biyun. Bugu da ƙari, an gano cewa Ursodiol zai iya yin niyya da kyau da kuma bi da manya da ƙananan gallstones a duka biyu, manyan allurai da ƙananan allurai. Chenodiol, a gefe guda, yana da tasiri kawai don rage girman ƙananan ƙananan gallstones a mafi yawan allurai.

Dangane da wani binciken daban-daban, chenodiol a ƙananan allurai yana da alaƙa da haɓakar haɓakar cholecystectomy.

 

Menene Matsalolin Matsalolin Chenodeoxycholic Acid?

Lokacin da aka wajabta chenodeoxycholic acid, ana ba da shawarar yin bibiyar mai haƙuri akai-akai. Kowace ziyara ta biyo baya ya kamata ya haɗa da gwajin jini tare da babban mayar da hankali akan enzymes hanta. Wannan shi ne saboda yanayin hepatotoxic na chenodeoxycholic acid. Za a iya raba illar illar chenodeoxycholic acid zuwa kashi biyar, bisa tsarin gabobin da galibin illar ke shafar:

 

Hematologic illa

An ba da rahoton wasu 'yan lokuta na sakamako masu illa na hematologic, tare da duk mutanen da abin ya shafa sun ba da rahoton raguwa mai yawa a cikin ƙwayar jinin jini. Mahimmanci bai taɓa raguwa a ƙasa da 3000 ba kuma duk da raguwar wannan, an yarda da maganin da kyau. Ba a yanke shawarar dakatar da CDCA foda ba ga kowane ɗayan waɗannan marasa lafiya kamar yadda wannan sakamako na gefe bai haifar da wani babban damuwa na kiwon lafiya ba.

 

Hanta illa

Chenodeoxycholic acid foda shine hepatotoxic wanda shine dalilin da yasa aka hana amfani da shi a cikin cututtukan hanta. Bugu da ƙari, hepatotoxicity na CDCA foda zai iya zama mai tsanani sosai cewa kulawa na yau da kullum na enzymes hanta yana da mahimmanci lokacin da aka fara magani. Ba a saba ganin waɗannan illolin idan an ɗauki matakan da suka dace kamar lura da aikin hanta. Yin amfani da chenodiol foda ba tare da mayar da hankali kan gwaje-gwajen aikin hanta ba zai iya haifar da rashin lafiyar hanta da cututtuka.

Alamun cututtukan hanta waɗanda zasu iya gabatar da kansu tare da hepatotoxicity na chendiol sune:

  • Yellow na idanu
  • Fata mai launin rawaya
  • Furowa mai launin duhu
  • Kasala da kasala da ba a saba gani ba
  • Abun ciki mai tsanani
  • Tashin zuciya da amai wanda baya warwarewa

 

Illolin ciki na ciki

Wadannan sakamako masu illa na iya bayyana a kowane lokaci yayin shirin jiyya duk da haka, an fi lura da su lokacin da aka fara magani. Wannan sakamako ne na yau da kullun kamar yadda yawancin magunguna lokacin da aka fara amfani da su, na iya haifar da haushi mai laushi. Kusan kashi 30 zuwa kashi 40 cikin 15 na mutanen da ke shan chenodiol sun ba da rahoton zawo wanda ke da kyau kuma ba mai tsanani ba. Sai kawai kashi XNUMX cikin XNUMX na waɗanda ke fama da zawo na dogaro da kashi sun buƙaci rage kashi. Wasu sun ba da rahoton ci gaba a cikin alamun bayyanar cututtuka bayan amfani da magungunan maganin zawo.

Da wuya, ana buƙatar dakatar da chenodiol lokacin da zawo ya yi tsanani kuma yana tare da ciwon ciki mai rauni. Kafin a daina shan magani, yana da mahimmanci don bambanta tsakanin ƙwanƙwasa zawo daga colick, ciwon ciki wanda zai iya kasancewa tare da gallstones. Rashin rikicewa na ƙarshe tare da tsohon da kuma dakatar da CDCA foda zai iya cutar da lafiyar gaba ɗaya.

 

Wasu daga cikin illolin gastrointestinal da ba su da yawa sun haɗa da,

  • Nuna da zubar
  • cramps
  • ƙwannafi
  • maƙarƙashiya
  • Dyspepsia
  • Ciwon ciki gabaɗaya
  • flatulence
  • anorexia

 

Matsalolin Cholesterol

Ana iya ganin kusan kashi 10 cikin ɗari na haɓakar ƙwayar cholesterol da ƙwayoyin cuta mara kyau, LDL, tare da amfani da foda na chenodeoxycholic acid. Wasu ƴan matan da ke shan bile acid suma sun ba da rahoton ƙaramin ƙara a cikin matakan triglycerides, tare da jimlar cholesterol da matakan LDL. Babu wani canji a HDL ko kuma an ba da rahoton kitse masu kyau.

 

Cire gallbladder ko ƙimar cholecystectomy

Mutanen da ke da gallstones da tarihin ciwon biliary akai-akai suna buƙatar hanyar cholecystectomy azaman maganin gallstones. Bugu da ƙari, waɗannan marasa lafiya kuma ba su iya jure wa babban adadin chenodeoxycholic acid foda kuma an ba su ƙananan allurai maimakon. Rashin iya jure wa babban kashi CDCA foda yana da, don haka, an hade shi tare da karuwar cholecystectomy.

Wadanne Matakai ne ake ɗauka don Tabbatar da Amintaccen Amfani da Ingantaccen Acid Chenodeoxycholic?

Ma'aikatan kiwon lafiya da masu aikin likita na gabaɗaya suna gudanar da ziyarar biyo baya don yin la'akari da duk wani tasiri mai tasiri na chenodeoxycholic acid foda don tabbatar da lafiyarsa da kuma ingancin foda.

 

A ina zan iya samun ƙarin bayani akan Chenodeoxycholic Acid Foda Siyar?

Don ƙarin bayani game da tallace-tallace na chenodeoxycholic acid foda a cikin girma, zaka iya amfani da albarkatun kan layi kamar shafukan yanar gizo na daban-daban na chenodeoxycholic acid foda masana'antun ko masana'anta.

 

Karin Bincike Game da Chenodeoxycholic Acid

A halin yanzu ana nazarin Chenodeoxycholic acid don wasu yuwuwar amfani da fili, baya ga takamaiman amfaninsa na biliary. Wani kamfanin fasahar kere-kere na Australiya a halin yanzu yana nazarin chenodiol a hade tare da maganin rage lipid, bezafibrate don maganin Hepatitis C.

 

Tambayoyin da

(1)Me ya sa chenodeoxycholic acid (chenodiol) kawai don zaɓaɓɓun mutane?

Chenodiol ne mai karfi bile acid wanda zai iya taimakawa wajen magance gallstones. Duk da haka, yana da hepatotoxic kuma yana iya haifar da cutar hanta mai tsanani. Wannan shine dalilin da ya sa ba a ba da shawarar ga masu ciwon hanta ba saboda alamun cutar na iya yin karin gishiri ta hanyar bile acid.

 

(2)Zan iya shan Chenodal (chenodiol) idan ina da ciki?

Ba a ba da shawarar yin amfani da chenodiol a lokacin daukar ciki ba saboda yiwuwar teratogenic na magani.

 

(3)Har yaushe zan dauki Chenodal (chenodeoxycholic acid)?

Ana iya ɗaukar Chenodal har zuwa shekaru biyu a lokaci guda, kuma yana iya ɗaukar chenodeoxycholic acid CDCA foda har zuwa shekara guda don rage alamun bayyanar cututtuka da kuma magance yanayin. Bayan yin amfani da CDCA foda na shekaru biyu, yana da mahimmanci don yin hutu.

 

(4)Me yasa ake tambayara don ganin mai bada sabis na lokaci-lokaci don gwaje-gwaje?

Mai ba da ku yana gwada enzymes na hanta da matakan cholesterol don tabbatar da cewa komai yana cikin kewayon al'ada, kuma chenodiol bai yi wani mummunan tasiri akan lafiyar ku gaba ɗaya ba. Saboda yanayin musamman hepatotoxic na CDCA foda da ikonsa na haifar da cutar hanta da sauri, mai ba da kayan abinci na chenodeoxycholic acid zai tambaye ku lokaci-lokaci don gwaje-gwaje. Hakanan an gano matakan cholesterol yana ƙaruwa tare da amfani da chenodiol, wanda shine wani gwajin da mai ba da ku zai nema daga gare ku.

 

(5)Wadanne magunguna zan guji yayin shan Chenodal (chenodiol)?

Lokacin shan Chenodiol, ya kamata ku nisantar da masu bile acid kamar su cholestyramine da colestipol kamar yadda zasu yi hulɗa tare da CDCA foda kuma suyi amfani da shi. Ba a ba da shawarar shan magungunan kashe jini kamar warfarin da coumadin, maganin hana haihuwa da estrogen a cikinsu, ko antacids da sauran magunguna masu ɗauke da aluminum. Idan kana shan duk wani kari na bitamin, kayan abinci na ganye, da shayi na ganye, ko kuma ka daina shan magani, ya kamata ka sanar da likitanka don tabbatar da cewa babu ɗayan magungunan ku na yanzu ko na baya-bayan nan da ke hulɗa da chenodiol.

 

reference

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