Anandamide (AEA) (94421-68-8)

Maris 15, 2020

Anandamide, wanda aka fi sani da N-arachidonoylethanolamine (AEA), mai ƙwayar ƙwayar ƙwayar ƙwayar cuta ne wanda aka samo daga …… ..

 


Status: A Mass Production
Naúra: 25kg / Drum

 

Anandamide (AEA) (94421-68-8) bidiyo

Anandamide (AEA) (94421-68-8) Sfasali

Product Name Anandamide (AEA)
Chemical Name Arachidonylethanolamide; N-Arachidonoylethanolamine; Anandamide (20.4, n-6);

N-Arachidonoyl-2-hydroxyethylamide; Arachidonoyl ethanolamide; AEA;

CAS Number 94421-68-8
InChIKey LGEQQWMQCRIYKG-DOFZRALJSA-N
Smile CCCCCC = CCC = CCC = CCC = CCCCC (= O) NCCO
kwayoyin Formula C22H37NO2
kwayoyin Weight 347.53
Monoisotopic Mass 347.282429 g / mol
Ƙaddamarwa Point N / A
tafasar Point 522.3 ± 50.0 ° C (Tsinkaya)
yawa 0.92 g / mL a 25 ° C (lit.)
Launi Rawaya mai haske
Syawan zafin rana -20 ° C
solubility ethanol: mai narkewa
Aikace-aikace Ana amfani dashi don ƙwaƙwalwa, motsawa, hanyoyin fahimta, sarrafa motsi, kula da jin zafi, motsawar ci da haihuwa.

 

Menene Anandamide (AEA)?

Anandamide, wanda aka fi sani da N-arachidonoylethanolamine (AEA), mai ƙwayar ƙwayar ƙwayar ƙwayar cuta ne wanda aka samo daga haɓakar rashin cin nasara na eicosatetraenoic acid (arachidonic acid. Yana da tsari mai kama da na tetrahydrocannabinol, mai aiki na cannabis. wanda aka lalata ta farko daga fatty acid amide hydrolase (FAAH) enzyme, wanda ke canza anandamide zuwa ethanolamine da arachidonic acid, A ƙarshe, Anandamide an haɗu a cikin neuron ta hanyar motsawar motsa jiki yana faruwa tsakanin arachidonic acid da ethanolamine a ƙarƙashin tsari na alli ion da cyclic monophosphate adenosidase. Shine mai share fage na rukunin abubuwa masu motsa jiki (Prostamides) waɗanda ke taka rawa a cikin ayyukan motsa jiki da yawa, ciki har da ci, da ƙwaƙwalwa, da ciwo, da baƙin ciki, da haihuwa.

Anandamide ya wanzu a cikin ƙwayoyin halitta da yawa, kamar su urchin roe roe, kwakwalwar aladu da hanta bera, da sauransu, amma lambarta kaɗan ce. Hakanan, masu binciken sun gano Anandamide da abubuwa biyu (N-oleoylethanolamine da N-Linoleylethanolamine) a cikin cakulan mai duhu. Anandamide ma ya wanzu a cikin wasu Hatattun hatsi, (farin burodi), Alkahol (musamman, amfani na yau da kullun ko shan giya), Tataccen sukari, Trans fats, Abincin da aka soya a cikin mai da kayan lambu da kuma Abincin da ba na organicabi'a wanda ke ɗauke da magungunan ƙwari da sauransu

A matsayin wani ɓangare na tsarin endocannabinoid (ECS), Anandamide an tsara shi azaman mai kula da homeostasis tare da wani aji na cannabis-kamar sunadarai 2-AG da masu karɓar cannabinoid na jiki baki ɗaya. Wannan tsarin ya kasance A cikin dukkanin hanyoyin katsewa. Anandamide yana taka rawa wajen daidaita halayen ciyarwa da motsawar jijiyoyi da nishadi, kiyaye jikinmu da hankalinmu a daidaito. Nazarin sun gano cewa motsin zuciyarmu, farin ciki, tsoro, damuwa, da ikon da za mu iya magance tashin hankali duk ana tsara su ta tsarin endocannabinoid, kuma cututtuka daban-daban daga schizophrenia zuwa ɓacin rai suna haɗuwa tare da matakan naƙasasshe na anandamide.

Anandamide, kama da THC, ɗan agonist ne na CB1R. Yana iya haifar da haɓaka mai yuwuwa ta hanyar “cika” kunna tsarin kwakwalwa. Ya kamata a lura cewa duk waɗannan tasirin na Anandamide suna da alama ana haɓaka su ta hanyar hana ilimin magani ta hanyar hana ta lalacewa. Binciken Anandamide na iya haifar da haɓaka sabon dangi gaba ɗaya na magungunan warkewa.

 

Anandamide (AEA) fa'idodi

Anandamide, wanda aka fi sani da “kwayar ni’ima”, mai haɓaka yanayi ne, neurotransmitter da endocannabinoid, wanda ke da ƙoshin lafiya da fa'idodi da yawa:

Anandamide yana rage saurin samar da ƙwayoyin kansa. A cikin 1998, wani rukuni na masana kimiyya na Italiya sun gano cewa anandamide na iya inganta neurogenesis kuma ya samar da sabbin ƙwayoyin jijiya, ta yadda yakamata a rage samuwar / ƙara darajar ƙwayoyin ciwon daji na nono.

Ikon Anandamide don haɓaka neurogenesis (samuwar sababbin ƙwayoyin cuta) yana taka rawa wajen sarrafa halayyar ciyarwa da haifar da motsawa da jin daɗi ga beraye. Wannan yana taimakawa rage alamomin damuwa da damuwa. Nazarin a cikin 2015 na mutane da beraye ya gano cewa babban matakin anandamide na iya haɓaka haɓaka yanayi da rage fargaba.

Bugu da kari, ikon anandamide ya daure ga masu karbar CB1 da CB2 zai kuma shafi tasirin hanyoyin ilimin lissafi da yawa, yana nuna kyawawan fa'idodi dangane da ƙwaƙwalwa, motsawa, tafiyar da hankali, sarrafa motsi, ikon ciwo, motsawar abinci da haihuwa.

 

Yadda ake kara yawan anandamide(AEA) matakan a jikin mutum?

Saboda anandamide yana da matsayi a matsayin mai kula da neurotransmitter, wakili na vasodilator da mai amfani da jini na jini na mutum, da kuma lafiyar lafiyar da amfanin kwakwalwa da aka nuna, zaku iya so ku ƙara matakin anandamide a jikin ku. Anan akwai wasu hanyoyi don ƙara matakan anandamide na ɗan lokaci a cikin jikin mutum:

- Motsa jikiyin

Binciken ya gano cewa bayan mintuna 30 kawai na gudu, anandamide (AEA) na mutane da karnuka ya karu. Don haka idan kuna son samun fa'ida mafi yawa, yi motsa jiki sau da yawa.

- Cin duhun cakulan

Cakulan duhu yana da babban adadin theobromine a cikin cakulan lafiya, kuma theobromine yana taimakawa wajen haɓaka samarwar anandamide a cikin kwakwalwa kuma yana rage jinkirinsa na ɗan lokaci.

- Cin duri baƙar fata

Black truffle (black naman gwari) ta halitta ya ƙunshi anandamide. Kodayake naman gwari ba zai iya amfani da anandamide a zahiri ba, masu binciken sun yi imanin cewa ana amfani da shi ne don jan hankalin dabbobi don su ci shi kuma su haifeshi.

- Samun hankali

Bincike ya nuna cewa lokacin da mutum yake cikin wani yanayi (wanda ake kira "mai gudana" ko "a wani yanki,") na babban natsuwa, aiki, da natsuwa, ba wai kawai za ku zama mai haɓaka ko ƙirƙirar ayyuka masu kyau a cikin kwakwalwar ku ba. yawancin sunadarai, kamar su serotonin, dopamine, endorphin da anandamide.

Bugu da ƙari, shayi, coriander da seleri kuma zasu iya taimakawa wajen haɓakar haɓakar anandamide.

 

reference:

  • Berger, Alvin; Crozier, Gayle; Bisogno, Tiziana; Cavaliere, Paolo; Innis, Sheila; Di Marzo, Vincenzo (15 Mayu 2001). "Anandamide da abinci: Hada arachidonate da docosahexaenoate yana haifar da ƙara matakan kwakwalwa na N-acylethanolamines daidai a cikin aladu". Ayyukan Cibiyar Kimiyya ta Kasa. 98 (11): 6402– Bibcode: 2001PNAS… 98.6402B. Doi: 10.1073 / pnas.101119098. PMC 33480. PMID 11353819.
  • El-Talatini MR, Taylor AH, Konje JC (Afrilu 2010). "Dangantaka tsakanin matakan plasma na endocannabinoid, anandamide, magungunan jima'i, da gonadotrophins yayin zagayen al'ada". Takin taki. Steril. 93 (6): 1989– doi: 10.1016 / j.fertnstert.2008.12.033. PMID 19200965.
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  • Mechoulam R, Fride E (1995). "Hanyar da ba a san ta ba zuwa ga kwayar cutar Cannabinoid ligands, anandamides". A cikin Pertwee RG (ed.). Cannabinoid masu karɓa. Boston: Cibiyar Nazarin Ilimi. shafi na 233– ISBN 978-0-12-551460-6.
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