Raw Lorcaserin HCL foda (846589-98-8)

Oktoba

Raw Lorcaserin hydrochloride foda shine mai karɓa na 2C (5-HT2C) mai karɓar agonist kuma ana ba da magani ta baki wanda ke inganta….


Status: A Mass Production
Naúra: 25kg / Drum
Capacity: 1380kg / watan

Raw Harshen HCL Mawasa (846589-98-8)

 

Raw Lorcaserin HCL foda (846589-98-8) Bayani

Product Name Raw Lorcaserin Hydrochloride foda
Chemical Name Raw Lorcaserin HCL foda, Lorcaserin
Brand Name BELVIQ
Drug Class 5-HT2C mai karɓar mai karɓa
CAS Number 846589-98-8
InChIKey ITIHHRMYZPNGRC-QRPNPIFTSA-N
kwayoyin FƘararraki C11H15Cl2N
kwayoyin Wtakwas 232.15
Monoisotopic Mass 231.058154899
Gyarawa Point  Babu bayanai akwai
Freezing Point Babu bayanai akwai
Half Half-Life Rabin rabi na lorcaserin ne kamar 11 hours.Lorcaserin foda an kawar da farko a cikin fitsari (92%) da kuma a cikin feces (2.2%)
Launi White foda
solubility  Rashin ruwa na ruwa: 0.0709 mg / ml
Storage Taikin zafi  -20 ° C.
Aaikace-aikace Magunguna mai karɓa na srorotonin 2C (HT2C) don asarar nauyi.Da rage cin abinci da kuma inganta zaman lafiya a tsakiya

 

Raw Lorcaserin Hcl foda (846589-98-8) Bayani

Raw Lorcaserin hydrochloride foda shine hydrochloride da aka samu ta hanyar tasirin lorcaserin foda tare da daidai da hydrochloric acid. An yi amfani dashi azaman maganin rigakafin kiba Lorcaserin hydrochloride shine mai karɓar mai karɓa na 5HT2c wanda aka nuna don amfani ga manya tare da BMI ≥30, ko waɗanda ke da BMI ≥27 kuma aƙalla yanayin da ke da alaƙa da nauyi kamar hauhawar jini, rubuta ciwon sukari na 2 ko dyslipidemia. yana haifar da jin daɗin ƙoshin lafiya, kuma ana tunanin kauce wa hazo na cututtukan zuciya na zuciya wanda ke haɗuwa da kunna masu karɓar 5-HT2B, yankin ƙwaƙwalwar da aka sani da taka muhimmiyar rawa wajen daidaita yunwa da cin abinci. Ta hanyar kunna waɗannan masu karɓar, Lorcaserin hydrochloride foda na iya rage yawan cin abinci ta rage rage ci kuma sa mutum ya ji daɗi ko da bayan cin abinci ƙasa da yadda aka saba. An amince da shi a yau ta hanyar FDA a cikin yanke shawara mai ban mamaki bayan shekaru 2 na bincike.

Ana ba da alamar samfurori mai gina jiki a cikin jiki mai saukin rage yawan karancin jiki (BMI na 30 kg / m2 ko mafi girma) kuma babba babba (BMI na 27 kg / m2 ko mafi girma) tare da akalla nau'in sharaɗɗa masu dangantaka da nauyi.

An yi amfani da man fetur na lantarki na Lorcaserin tare da abinci da motsa jiki don bi da kiba. Ana amfani da shi a wasu lokuta da kiba wanda zai iya dangantaka da ciwon sukari, high cholesterol, ko cutar hawan jini.

Lorcaserin hydrochloride ba za ta bi da wani yanayin lafiya ba (kamar cututtukan zuciya, ciwon sukari, hawan jini). Ci gaba da shan wasu magunguna da likitanku ya tsara don biyan waɗannan yanayi.

Hanyoyin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin {asashen {asar Amirka

Kodayake ba'a san ainihin ainihin aikin ba, an yi imanin ya ƙunshi zaɓin zaɓi na masu karɓa na 5-HT2C a cikin ƙananan neorexigenic pro-opiomelanocortin ne a cikin tsakiya na hypothalamus. Wannan yana haifar da rage yawan abincin abinci da rashin jin daɗi ta hanyar inganta sakin hormone na alpha-melanocortin, wanda ke aiki akan masu karɓa na melanocortin-4.

Lorcaserin hydrochloride foda yana aiki ta hanyar sarrafa abinci - musamman ta hanyar kunna masu karɓar kwakwalwa don serotonin, wani ɗan kwayar cutar da ke haifar da jin daɗi da gamsuwa. Samun abinci yana sarrafawa ne ta hanyar cibiyar satiety, wanda ke cikin kwayar iska ta hypothalamus da cibiyar yunwa da ke cikin hypothalamus na gefe. Ayyuka iri-iri daga manyan cibiyoyi da hanyoyin hanji suna haɗuwa a tsakiya, inda nau'ikan nau'ikan jijiyoyi biyu masu sarrafa abincin suke. Da fari dai, ƙungiyar mai cin abinci mai haɓaka abinci mai haɓaka furotin da ke da alaƙa da agouti da neuropeptide Y; kuma na biyu, ƙungiyar hana cin abinci da ke ƙunshe da hodar iblis da amphetamine da aka tsara kwafi (CART) da ƙwayoyin cuta na pro-opiomelanocortin (POMC). POMC ya ƙunshi masu karɓar 5-HT 2C, wanda lokacin da aka kunna su yana fitar da hawan mai kara alpha-melanocyte (alfa-MSH). Paraaƙarin tsakiya yana ƙunshe da masu karɓar melanocyte 4 (MC4R) wanda ke hana ci abinci a cikin allurai na kwayoyi lorcaserin hydrochloride foda yana aiki azaman mai zaɓin 5-HT 2C agonist akan ƙwayoyin POMC, wanda hakan yana haifar da sakin alfa MSH. Arin alfa MSH yana aiki akan MC4R a cikin tsakiya mai mahimmanci a cikin hypothalamus, wanda ke haifar da rage yawan ci. A cikin magungunan asibiti, lorcaserin hydrochlorider yana aiki akan 5-HT 2B da masu karɓa na 5-HT 2A.

amfanin na ƙwayar Lorcaserin Hcl (846589-98-8)

  • Lissafin Harkokin Cizon Cizon Casa ne mai amfani da agonist mai karɓar 5-HT2C wanda ake zaton zai rage yawan abincin abinci ta tsakiyar tsarin POMC. Lorcaserin HCL foda amfani:
  • Ana amfani da furotin na Cizon Lakaci tare da abinci da motsa jiki don bi da kiba.
  • Ana yin amfani da ƙwayar launi na LCCC a lokacin amfani da cutar da za a iya danganta da ciwon sukari, high cholesterol, ko cutar hawan jini.
  • Lissafin Cizon Labaran Casa ne ba za ta bi da wani yanayin lafiya ba (kamar cututtukan zuciya, ciwon sukari, hawan jini).

Shawarar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (846589-98-8) Dosage

Lorcaserin HCL foda ya zo a cikin nau'i na kwamfutar hannu kuma ana ɗauka sau 1-2 sau ɗaya a rana, tare da ko ba tare da abinci ba. Dole ne a yi amfani da Lorcaserin tare da rage rage cin abincin kalori da shirin motsa jiki.

Halin da aka ba da shawarar na lorcaserin hcl foda shine 10 MG da ake gudanarwa ta bakin sau biyu a rana. Ana iya ɗaukar Lorcaserin ba tare da la'akari da abinci ba. Lorcaserin hcl ya kamata a dakatar da shi a cikin marasa lafiya waɗanda suka kasa cimma aƙalla nauyin hasara na 5% a mako 12 tun da waɗannan marasa lafiya ba za su iya fuskantar asarar nauyi mai ma'ana tare da ci gaba da jiyya ba.

Side effects na ƙwayar Lorcaserin Hcl (846589-98-8)

Ana amfani da furotin Lorcaserin Hcl don maganin kulawar nauyi na yau da kullun a cikin manya tare da bayanan girman jiki (BMI) na 30 ko mafi girma (obese) azaman ƙari ga rage-kalori rage cin abinci da motsa jiki. Hakanan an yarda da amfani da manya tare da BMI na 27 ko mafi girma (mai nauyi) kuma waɗanda ke da aƙalla yanayin haɗuwa da nauyi kamar hawan jini (hauhawar jini), ko babban cholesterol (dyslipidemia). Koyaya, shima yana iya samun wasu tasirin. Kamar yadda ke ƙasa:

 Tshi ne sakamako mafi rinjaye:

  • -Bajada,
  • -Dizziness,
  • -Fatigue,
  • -Nausea,
  • -Da baki,
  • -Constipation, da kuma
  • -Hypoglycemia (ƙananan jini sugar).

 Sauran ƙananan cututtukan da ke hade da lorcaserin sun hada da:

  • -Waɗanda ba a iya amfani da shi ba,
  • -Ya canzawa a hankali ko ƙwaƙwalwa,
  • -Munanan matsalolin,
  • -Depression ko tunani na kashe kansa,
  • -Faɗannan abubuwa,
  • -Ka sa zuciya,
  • -Dajin cikin ƙwayar jini, kuma
  • -An karuwa a cikin hormone, prolactin.