Cycloastragenol foda (78574-94-4)

Afrilu 17, 2020

Cycloastragenol wani abu ne wanda yake da kwarin gwiwar inganta tsufa daga cikin kayan abinci a kasuwa.

Cycloastragenol foda (78574-94-4) bidiyo

Lankanars foda Sfasali

Product Name Cycloastragenol foda
Chemical Name N / A
nufin abu ɗaya ne astrannawarranin

cyclogalegigenin

GRN510

CAG

Drug Class N / A
CAS Number 78574-94-4
InChIKey WENNXORDXYGDTP-UOUCMYEWSA-N
kwayoyin FƘararraki C30H50O5
kwayoyin Wtakwas 490.7 g / mol
Monoisotopic Mass 490.365825 g / mol
tafasar batu N / A
Freezing Point N / A
Half Half-Life N / A
Launi fararen fata
Solubility DMSO: 10 MG / ML, bayyana
Storage Taikin zafi 2-8 ° C
Aaikace-aikace Cycloastragenol mai karfi ne mai kunnawa telomerase. Hakanan, yana da alaƙa da anti-tsufa a cikin maganin gargajiya na kasar Sin.

Overview

Cycloastragenol wani abu ne wanda yake da kwarin gwiwar inganta tsufa daga cikin kayan abinci a kasuwa. Hakanan ana amfani dashi a cikin kulawar fata da kayan kwalliyar kwalliya. Cycloastragenol an fara tallata shi ne a cikin kayan abinci a cikin Amurka a 2007 a cikin sunan TA-65, wannan shine dalilin da yasa TA 65 ko TA65 har yanzu shine sunan da aka fi sani ga cycloastragenol.

Menene Cycloastragenol?

Cycloastragenol kwayar halitta ce da aka samo daga ganye daga Astragalus membranaceus. An yi amfani da ganye na Astragalus a cikin magungunan Sinawa tsawon ƙarni. Kasar Sin ta yi ikirarin cewa Astragalus na iya tsawaita rayuwa kuma ana amfani da shi don magance gajiya, rashin lafiyar jiki, mura, cututtukan zuciya da ciwon suga.

Cycloastragenol yana ɗayan kayan aiki masu aiki a cikin Astragalus. Cycloastragenol yana da nau'ikan sunadarai masu kama da na kwayoyin Astragaloside IV, amma yana da ƙarami kuma mafi mahimmancin kwayoyin halitta, yana ba da damar ƙananan matakan. An riga an yi amfani dashi azaman immunostimulant saboda iyawarsa na haɓaka haɓakar lymphocyte T. Koyaya, shine keɓaɓɓen kayan anti-tsufa waɗanda ke da babbar sha'awa ga al'umman kimiyya.

Cycloastragenol yana ƙarfafa gyaran lalacewa ta DNA ta kunna telomerase, wani enzyme na nucleoprotein wanda ke ɗaukar kira da haɓaka DNA na telomeric. Telomeres an yi su da filastik na bakin ciki kuma ana samun su a ƙarshen ƙwayoyin chromosomes. Kula da kwanciyar hankalirsu yana bawa sel damar guji fitowar ƙwayar cuta da haɓakawa mara iyaka ta 'iyakar Hayflick'. Telomeres ya gajarta tare da kowane zagayen rarraba sel, ko kuma lokacin da aka sa masa wahala matsalar iskar shaka. Har yanzu, wannan ya zama hanyar da ba za'a iya kawar da tsufa ba.

Hanyoyin aikin Cycloastragenol

Yawancin karatu sun nuna cewa rage cin gaban kwayar halittar kwayar cuta yana da alaƙa da cututtukan da ke da alaƙa da shekaru (cututtukan zuciya, cututtukan zuciya, da sauransu) kuma yana tsinkayar mutuwa ta gaba ga tsofaffi. Telomeres ya gajarta tare da kowane zagayen rarraba sel, ko kuma lokacin da aka sa masa wahala matsalar iskar shaka. Har yanzu, wannan ya zama hanyar da ba za'a iya kawar da tsufa ba.

Telomerase shine tsohuwar enzyme nucleoprotein wanda ke ɗaukar kwayar halitta da haɓaka DNA na telomeric kuma yana ƙarfafa gyaran lalacewa na DNA.

Cycloastragenol yana aiki da haɓakar wannan enzyme, don haka yana rage rage ƙwayoyin kwayoyi kuma yana ƙaruwa da lambobi. Ta wannan hanyar, yana ba da izinin tsawan telomeres kuma a sakamakon haka, yana haɓaka rayuwar rayuwar tantanin halitta.

Saboda ƙarancin ƙwayar ƙwayar jikinta, Cycloastragenol yana wucewa cikin sauƙi ta bangon hanji. Ingantaccen kimantawa yana ba da damar mafi inganci, koda a ƙarancin kashi. Ationaddamar da yau da kullun ko dai a kan kansa, ko a haɗuwa ko a musanya tare da, astragaloside IV, don haka zai taimaka wajen dakatar da tsufa kuma a zahiri ya kara tsawon rayuwa.

Lankanars amfanin

Astragalus membranaceus yana cikin mafi mahimmancin ganye a cikin Tarihin Magungunan gargajiya na gargajiya kamar magungunan gargajiya don magance gajiya, ciwo, cututtukan fata, cutar kansa, zazzabin cizon sauro, ƙwayar bugun jini, tsawon lokaci da sauransu Cycloastragenol kwayoyin ne da aka samo daga ƙwayoyin Astragalus membranaceus. Koyaya, mahimman fa'idodi na cycloastragenol foda suna matsayin rigakafin tsufa da tasirin tallafin rigakafi.

Lankanars da tallafin rigakafi

Za'a iya amfani da Cycloastragenol don kiyaye tsarin rigakafi, ƙwayoyin cuta, da antiinflammatory, don guje wa cututtukan yau da kullun da cututtukan jijiyoyin jiki na sama. Ana amfani dashi azaman mai haɓakar rigakafi saboda kasancewa yana iya haɓaka yaduwar cutar ta lymphocyte. Koyaya, abin da masana kimiyya ke ƙara nuna sha'awa shine kyakkyawan juriya. Cycloastragenol yana ƙarfafa DNA don gyara lalacewar ta hanyar fara amfani da telomerase kuma yana ba da izinin ƙirar nukiliya ta mamaye kira da haɓakar DNA na telomere.

Lankanars da tsufa

Anti-tsufa shine mafi yawan amfanin cycloastragenol. Cycloastragenol ba wai kawai yana jinkirta tsufa ne na mutum ba, amma bugu da hasari yana haɓaka rigakafi, tsoratar da gubobi, kiyaye ƙwayoyin zuciya, akasarinsu sunadarai daga astragaloside (Astragaloside Ⅳ) hydrolysis.

Sauran fa'idodin Cycloastragenol

  1. cycloastragenol foda yana da tasiri akan rage damuwa da kare jiki daga damuwa daban-daban, da suka hada da damuwa ta jiki, hankali, ko tausayawa;
  2. cycloastragenol foda yana dauke da antioxidants, wanda ke kare sel daga lalacewa ta hanyar tsattsauran ra'ayi;
  3. cycloastragenol foda yana da tasiri a rage karfin hauhawar jini, magance cutar sukari da kare hanta.

Lankanars foda sakamako masu illa

Har zuwa yanzu, babu wani rahoto ko sake dubawa game da mummunar tasiri ko contraindication shan ƙarin cycloastragenol.

Lankanars kari sashi

Cycloastragenol ne kwatankwacin sabo kuma bawai samfuran abinci masu yawa bane a kasuwa, kuma babu wani shawarar da za'a bayar dashi. Dangane da kwarewarmu, satin ya sha bamban da dalilai daban-daban, shekaru daban-daban. Tabbas cycloastragenol yana da ƙarfi sosai fiye da Astragaloside IV wanda shawarar da aka bayar dashi shine 50mg kowace rana. Duk da yake don cycloastragenol, dosing daga 10mg zuwa 50mg duk yayi kyau. Tsohuwar tana buƙatar ɗaukar fiye da tsofaffi masu shekaru. Wasu suna ba da shawarar farawa daga 5mg kowace rana, sannan ƙara a hankali. Tun da cycloastragenol shine asalin cirewa, zai iya ɗaukar lokaci don ganin tasirin, kusan watanni shida.

Lankanars aminci

Wasu sun ba da labari ga Cycloastragenol a matsayin wakili na anti-tsufa mai banmamaki. Karatuttukan farko sun bayyana mai inganci, suna nuna cewa yana da ikon haɓaka telomere, kodayake har yanzu akwai ƙarancin ingancin binciken da aka yi wa magina. Bugu da kari, akwai wasu damuwa cewa shan Cycloastragenol na iya kara hadarin wasu cututtukan daji. Koyaya, nazarin bincike bai sami damar iya tabbatar da duk wani haɗarin cutar kansa da ke hade da amfani da Cycloastragenol ba.

Cycloastragenol yayi kama da alkawarin inganta tsufa. Duk da yake ba a tabbatar da haɓaka rayuwa ba duk da haka an nuna shi don rage nau'ikan shekaru masu alaƙa da rayuwar aure. Bugu da kari an nuna shi don rage alamun tsufa kamar su layi mai kyau da alagammana. Hakanan yana iya rage haɗarin cututtukan degenerative kamar Alzheimer, Parkinson's, retinopathies, da cataracts.

Lankanars foda yana amfani da aikace-aikace

Ana amfani da Cycloastragenol don magani, sarrafawa, rigakafin, & haɓaka daga waɗannan cututtuka, yanayi da alamu:

  • kumburi
  • apoptosis
  • Homeostasis rikice-rikice
  • Hakanan za'a iya amfani da Cycloastragenol don dalilai waɗanda ba a lissafta su ba.

Anyi amfani da foda cycloastragenol foda a ƙasa:

  1. Ana amfani dashi a cikin filin abinci, galibi ana amfani dashi azaman abincin;
  2. Aiwatar da shi a cikin samfurin samfurin kiwon lafiya, wannan cirewar yana taimakawa jikin mutum;
  3. Aiwatar da shi a cikin filin kwaskwarima, a matsayin nau'i na albarkatun ƙasa, yana iya haɗa kayan kwalliyar halitta.

reference:

  • Abubuwan da suka dace da rigakafin tsufa na cycloastragenol wanda aka samar ta biotransformation.Chen C, Ni Y, Jiang B, Yan S, Xu B, Fan B, Huang H, Chen G.Nat Prod Res. 2019 Sep 9: 1-6. doi: 1080 / 14786419.2019.1662011.
  • Cycloastragenol: candidatean takarar marubuta mai ban sha'awa game da cututtukan da suka danganci shekaru.Yu Y et al. Fitar da su Med. (2018) Maganin rigakafin tsufa na cycloastragenol wanda aka samar da biotransformation. Chen C, Ni Y, Jiang B, Yan S, Xu B, Fan B, Huang H, Chen G. Nat Prod Res. 2019 Sep 9: 1-6. doi: 10.1080 / 14786419.2019.1662011
  • Cycloastragenol na iya yin watsi da kunna ayyukan STAT3 da inganta paclitaxel-induced apoptosis a cikin sel na ciki.Hwang ST, Kim C, Lee JH, Chinnathambi A, Alharbi SA, Shair OHM, Sethi G, Ahn KS. 2019 Jun
  • Astragaloside VI da cycloastragenol-6-O-beta-D-glucoside suna inganta warkar da rauni a cikin viro da vivo.Lee SY et al. Fazaman. (2018)