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Meclofenoxate (Centrophenoxine) (51-68-3)

Meclofenoxate (Centrophenoxine), wanda aka sayar a ƙarƙashin alamar alama Lucidril, yana ɗayan farko kuma mafi yawan bincike ……


Status: A Mass Production
Naúra: 25kg / Drum

description

Meclofenoxate (Centrophenoxine) foda Sfasali

Product Name Meclofenoxate (Centrophenoxine) (51-68-3)
Chemical Name Clophenoxate;
Meclophenoxate;
Clofenoxin;
Proseryl;
2- (dimethylamino) ethyl 2- (4-chlorophenoxy) acetate
Brand Name N / A
Drug Class Abubuwan Anti-Allergic Agents, Antineoplastic Agents, Tsarin tsufa
CAS Number 51-68-3
InChIKey XZTYGFHCIAKPGJ-UHFFFAOYSA-N
kwayoyin FƘararraki C12H16ClNO3
kwayoyin Wtakwas 257.71 g / mol
Monoisotopic Mass 257.081871 g / mol
tafasar batu 345.941 ° C a 760 mmHg
Freezing Point N / A
Half Half-Life 2-4 sa'o'i
Launi farin
Solubility Rashin ruwa: 2.9 mg / mL
Storage Taikin zafi -20 ° C
Aaikace-aikace Centrophenoxine foda yayi amfani da magungunan nootropics da kuma karin abinci.

Maimaitawar Meclofenoxate (Centrophenoxine)

Meclofenoxate (Centrophenoxine), wanda aka sayar a ƙarƙashin samfurin alama Lucidril, yana ɗayan farkon kuma mafi yawan binciken nootropics ko magungunan da ake kira "smart". Sanannen sananne ne kuma mai girmamawa wanda ya tabbatar da kansa tsawon shekaru fiye da biyar na amfani da gwajin asibiti.

An samo asali ne a cikin 1959 ta masana kimiyya a Cibiyar Nazarin Harkokin Ilimin Kimiyya ta Faransa a matsayin magani ga cutar Alzheimer, isasshen kwararar jini zuwa kwakwalwa, ‍ da faduwa da ke da alaƙa da tsufa, wannan ƙwaƙwalwar an yi amfani dashi sosai don magance cututtukan da ke da dangantaka da tsufa, irin wannan kamar yadda Alzheimer da dementia. Hakanan masu amfani da lafiya suna amfani dashi don haɓaka ƙwaƙwalwar ajiya da aiki tare da haɓaka aiki da haɓaka lafiyar kwakwalwa gaba ɗaya.

Bincike ya nuna centrophenoxine foda don zama mai ƙarfafa ƙwaƙwalwar ƙwaƙwalwa mai ƙarfi da wakili na tsufa.

A cikin Turai, an wajabta don magance asarar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa, amma ana samunsa akan mai azaman azaman karin abinci a cikin Amurka da Kanada, inda aka saba amfani dashi don haɓakar haɓaka ƙwarewa.

Menene Meclofenoxate (Centrophenoxine)?

Anyi amfani da Centrophenoxine a matsayin ƙarin kayan abinci don yuwuwar ƙwaƙwalwar ajiyarsa.

Centrophenoxine shine haɗin sunadarai biyu:

Dimethyl-aminoethanol (DMAE), wanda shine abu na halitta wanda aka samo a wasu abinci (kifi, abincin teku) da adadi kaɗan a cikin kwakwalwa. Tushen choline kuma yana da tasirin kwakwalwa.

Parachlorphenoxyacetic acid (pCPA), sigar roba ce ta kwayoyin halittu masu tasowa da ake kira “auxins”.

DMAE shine babban bangaren aiki a wannan magani. DMAE baya ƙetare shingen jini-kwakwalwa da kyau. Koyaya, a cikin centrophenoxine, zai iya wucewa tsakanin shinge-kwakwalwa kuma ya shiga cikin kwakwalwa yadda yakamata

Da zarar ya shiga cikin jiki, wani kashi na centrophenoxine ya rushe zuwa DMAE da pCPA a cikin hanta. DMAE sannan ya canza zuwa choline, yayin da ragowar centrophenoxine kewaya ko'ina cikin jiki.

Meclofenoxate (Centrophenoxine) fa'idodi

Centrophenoxine na iya taimakawa wajen yakar cutar kansa.

Centrophenoxine na iya taimakawa bayyanar cututtuka na rashin jinkirin dyskinesia.

Centrophenoxine yana haɓaka ƙwaƙwalwar ajiya da koyo, yana iya inganta ƙwaƙwalwar ajiya a cikin marasa lafiya na dementia.

An nuna Centrophenoxine don haɓaka samuwar, adanawa, da maido da tunanin. Improvedwaƙwalwar ƙwaƙwalwa yana inganta yayin da muke da matakan girma na acetylcholine. Ganin cewa Centrophenoxine yana haɓaka yawancin ayyukan cholinergic, ɗayan abubuwan da aka samar shine choline, tsakanin sauran nau'ikan phospholipids.

Inganta Ayyukan Kwarewa

Za'a iya amfani da Centrophenoxine azaman prodrug na DMAE kuma wannan yana da mahimmanci, saboda wannan ƙwayar kwayar halitta tana da tasiri sosai wajen rage sauran abubuwan haɗarin ƙwayoyin cuta a cikin kwakwalwa wanda zai iya haifar da raguwa mai mahimmanci a cikin ayyukan hankali. Da an cire waɗannan kwayoyin, tsofaffi na iya rage tsufa su kuma juya wasu sakamakon illa na tsufa.

Centrophenoxine yana da anti-tsufa da Kayan aikin Neuroprotective

An nuna Centrophenoxine don haɓaka rayuwar rayuwar beraye har zuwa 50%.

Centrophenoxine yana inganta Mood da Motsi, yana iya taimakawa rage damuwa.

Nazarin dabbobi suna ba da shawarar cewa centrophenoxine yana da tasirin rigakafin damuwa.‍

Meclofenoxate (Kwayan Kwayoyin) metabolism

Centrophenoxine galibi yana aiki ne ta hanyar isarwa da haɓaka ayyukan choline. Choline shine farkon aikin acetylcholine, mahimmanci ne mai mahimmanci wanda ba shi da iyaka wanda ke da alaƙa da jijiyoyin ƙira, filastik, da ƙwaƙwalwa. Ba a bayyana yadda daidai centrophenoxine yake haɓaka matakan choline da acetylcholine ba, amma ana tunanin cewa ko dai a dabi'ance zai rushe zuwa choline ko kuma ya canza zuwa phospholipid na matsakaici wanda ake amfani dashi don samar da acetylcholine. Ba tare da la'akari da hanyar ba, ikon cholinergic shine ya sa centrophenoxine irin wannan ƙarfin ƙwaƙwalwar mai ƙarfin nootropic a cikin ikon kansa.

Baya ga haɓakar haɓakar aikin acetylcholine, an san centrophenoxine a matsayin mai ƙarfin lantarki mai ƙarfin motsa jiki wanda ke ƙarfafa ayyukan kwakwalwa gaba ɗaya ta hanyar inganta yawan glucose da haɓakar haɓakar oxygen. Yin hakan, centrophenoxine yana sa aikin kwakwalwa ya fi dacewa, ta haka ne inganta mayar da hankali, maida hankali, da kuma fahimtar tunani, kawar da abin da ake kira hazo na kwakwalwa. A matsayin mai maganin antioxidant mai karfin gaske, yana magance radicals kyauta, yana fitar da gubobi kuma yana shiga cikin gyaran sel da suka lalace. Aƙarshe, yana jujjuyawar tsufa na hankali ta hanyar ragewa ko kawar da ginin samfuran kayan haɓaka wanda aka ɗauka da cewa "lalacewa ne da alamu na lalacewa."

Meclofenoxate (Centrophenoxine) sakamako masu illa da aminci.

Ana ɗaukar Centrophenoxine amintacce kuma mara amfani mai guba. An yi amfani da shi na kusan shekaru 50 ba tare da wasu manyan-sakamako masu illa ba.

An ce ya zama magani mai haƙuri ga yawancin tsofaffi masu lafiya da kuma dattijan da ke fama da rashin ƙwaƙwalwar ajiya.

Koyaya, wasu masu amfani sun dandana mai sauƙi da ƙananan sakamako masu illa, gami da tashin zuciya, ciwon kai, al'amuran gastrointestinal, da rashin bacci.‍

Ba a ba da shawarar Centrophenoxine ga mata masu ciki ba saboda abun ciki na DMAE.

Meclofenoxate (Kwayan Kwayoyin) foda sashi

Centrophenoxine yana samuwa a kan kanta a cikin capsules wanda ke ɗauke da 200-300 MG kowane. Gwajin asibiti wanda ya gwada tasirin centrophenoxine akan ayyukan fahimi sunyi amfani da allurai na yau da kullun

1,200 MG a cikin tsofaffi masu lafiya da allurai har zuwa 2,000 MG a cikin masu fama da cutar dementia.

stacking

Centrophenoxine tushe ne mai kyau na choline, zaku iya samun sa a cikin tariyoyi masu yawa na nootropic - wasu daga cikin abubuwanda aka saba dasu sune Noopept da Racetams.

Centrophenoxine da Aniracetam Stack

Anan ga misalin tarin centrophenoxine wanda ya hada da shahararen aniracetam na racetam don bunkasa riƙewar ƙwaƙwalwa, yanayi, kerawa, yayin rage damuwa.

1-2x a rana

250 mg Centrophenoxine

750 mg Aniracetam

Centrophenoxine da Noopept Stack

Anan ga misalin tarin centrophenoxine tare da Noopept, wannan tari zai iya inganta ƙwaƙwalwar ajiya da koyo, yayin samar da kaddarorin neuroprotective.

1-2x a rana

250 mg Centrophenoxine

20 mg Noopept

reference:

  • A kan aikin kwantar da ilimin halittar jiki a cikin kwayar halittar haihuwa da yawa yayin tsufa da kuma sakamakon centrophenoxine. A bita. Zs-Nagy I et al. Arch Gerontol Geriatr. (1989)
  • Magungunan Cholinergic don maganin diski-diski dardkinesia. Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H. Cochrane Database Syst Rev. 2018 Mar 19
  • Ayyukan cytotoxic na alkylating jamiái a gaban centrophenoxine da samfuran hydrolysis. Sladek NE. J Pharmacol Exp Ther. 1977 Dec
  • Iyakar aikin antitumor na cyclophosphamide ta centrophenoxine. Kanzawa F, Hoshi A, Tsuda S, Kuretani K. Gan. 1972 Aug
  • Centrophenoxine: tasirin akan ƙwayar dabba mai tsufa Nandy K et al. J Am Geriatr Soc. (1978)
  • Bambancin sakamakon meclofenoxate akan asarar ƙwaƙwalwar ajiya a cikin tsofaffi. Marcer D et al. Tsufa. (1977)

BATSA DA TATTAUNAWA:

Ana Samun Wannan Abubuwan ne Don Amfani da Bincike Kawai. Sharuɗɗan Siyarwa suna Aiwatarwa. Ba don Amfani da Dan Adam bane, ko Likita, dabbobi, ko Amfani na Gida.


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