Tadalafil foda video
Bayanan Basan
| Product Name | Tadalafil foda |
| Chemical Name | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione |
| Brand Name | Cialis, Adcirca |
| Drug Class | PAH, PDE-5 Masu hanawa; Magunguna masu ƙwayar cuta ta 5 Enzyme |
| CAS Number | 171596-29-5 |
| InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
| Kwayoyin halitta FƘararraki | C22H19N3O4 |
| Kwayoyin halitta Wtakwas | 389.4 |
| Monoisotopic Mass | 389.138 g / mol |
| Gyarawa Point | 298-300 ° C |
| Freezing Point | 2 ℃ |
| Half Half-Life | 17.5 hours |
| Launi | White zuwa Off-White Cyrstalline Solid |
| Solubility | Narkewa cikin DMSO (78 mg / ml a 25 ° C), methanol, ruwa (<1 mg / ml a 25 ° C), dichloromethane, da ethanol (<1 mg / ml a 25 ° C) |
| Storage Taikin zafi | Adana a zazzabin ɗaki tsakanin 59 ° F da 86 ° F (15 ° C da 30 ° C). Kada a adana wannan magani a wuraren danshi ko damshi. |
| Tadalafil Aaikace-aikace | raw Tadalafil foda tablets, Sexual candy, Sex coffee, etc. |
Tadalafil Foda
Dasfunction Erectile cuta ce ta yau da kullun ta maza a cikin maza wanda ke shafar kusan 52 bisa dari na maza sama da shekaru 18, a duk duniya. Bambanci a cikin ƙarfi, lalacewar erectile galibi yana haifar da raguwar zub da jini zuwa jijiyoyin jini na azzakari, wanda shine babban matakin samar da tsage.
Cutar tabarbarewa cuta ce gaba ɗaya mai iya sarrafawa da warkarwa tare da magunguna daban -daban waɗanda ke nufin enzymes na musamman a bangon jijiyoyin jini na azzakari. Ofaya daga cikin magunguna masu ƙarfi don ED shine Tadalafil foda tare da rabin rayuwar 17.5 hours.
Menene Tadalafil Foda?
Tadalafil Foda yana cikin rukunin magunguna masu motsa jima'i saboda magani ne wanda aka tsara don maza sama da shekaru 18, suna fama da larurar rashin ƙarfi. Tadalafil, ko (6R-trans) -6- (1,3-benzodioxol-5-yl) -2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1 ＇, 2＇: 1,6 , 3,4] pyrido [1,4-b] indole-XNUMX-dione magani ne mai kama da Sildenafil ko Viagra, a aikace, amma daban a tsari. Tadalafil kuma ya bambanta da na yau da kullun maganin rashin ƙarfi, Viagra, cikin ƙarfi kamar yadda ya fi ƙarfi da inganci fiye da na ƙarshe.
Tadalafil Foda magani ne na hana PDE5, wanda ke nufin cewa yana kaiwa hari ga PDE5 enzyme da aka samu a cikin sassan tsokar tsoka na jijiyoyin jini na azzakari. Aikin hana maganin yana da fa'ida sosai kamar yadda babban manufar enzyme shine haifar da vasoconstriction, wanda a cikin jijiyoyin jini na azzakari, yana haifar da raguwar zub da jini kuma saboda haka lalacewar erectile.
Tadalafil Foda ne Pharmax Lifesciences ya kera shi kuma ana iya amfani da shi don maganin fiye da tabarbarewa. Hakanan an ba da umarnin Tadalafil Foda ga mutanen da ke fama da matsanancin hauhawar jini na prostatic har ma da hauhawar jini na huhu. Koyaya, Tadalafil Foda ba shi da tasiri a cikin lura da wasu cututtukan tashin hankali na jima'i a cikin maza da mata.
Siffofin Tadalafil
Tadalafil shine mai hana PDE5 mai ƙarfi, yana samuwa a cikin nau'ikan daban -daban da allurai, yana sauƙaƙa amfani da shi ga marasa lafiya. Ana samun maganin a cikin nau'in kwayoyi ko capsules, tare da sashi na 5 MG, 10 MG, da 25 MG. Yana da mahimmanci a lura cewa sashi na Tadalafil ya bambanta dangane da kamfanin masana'anta.
Hakanan ana samun Tadalafil a cikin foda, kodayake galibi ana siyar dashi don amfanin masana'antu. Wannan shine babban dalilin da ke bayan Tadalafil Powder babban siyayya ya shahara sosai da wannan nau'in maganin. Yawancin lokaci ana siyar da wannan fom ɗin a cikin kwantena na 25 kg zuwa 50 kg, gwargwadon abin da ake buƙata.
Janar din dosage for Tadalafil powder, to start with, is 10 mg. The maximum dosage, within 24 hours, is 20 mg, and exceeding this dosage is not recommended.
This medication is safe for human consumption as it has received FDA ta yarda and approval from Indian, Canadian, Australian, and British Health authorities. The FDA approved the use of Tadalafil pills in the year 2002, and soon after, tadalafil powder use was approved by FDA as well.
Tadalafil masana'antar kera foda ta yi iƙirarin ƙera keɓaɓɓen magani tare da madaidaicin madaidaici. Masu kera suna da mafi girman martaba ga amincin ɗan adam, wanda aka bayyana sarai a cikin ƙarfi, aminci, da ingancin samfurin ƙarshe.
Yaya Tadalafil Foda ke Aiki?
Tadalafil Foda ya ƙunshi Tadalafil, wani mai hana PDE5 mai hanawa wanda GlaxoSmithKline ya fara bincike da ƙera shi bayan gano Sildenafil, irin wannan fili. Sildenafil, a gefe guda, an fara bincikensa azaman maganin angina da hauhawar jini amma duk binciken ya lalace bayan sakamakon da ya gaza a farkon matakan binciken. Koyaya, akan bita, an gano cewa Sildenafil na iya iya samar da kayan gini idan an yi wa marasa lafiya da kyau ta hanyar jima'i.
Kamar yadda sildenafil shine mai hana PDE5, GlaxoSmithKline ya yanke shawarar yin bincike mai zurfi a cikin mahadi tare da irin wannan aikin kamar Sildenafil. Wannan binciken ya haifar da ganowa sannan ci gaban Tadalafil.
Tadalafil shine mai hana PDE5 mai ƙarfi tare da rabin rayuwar sa'o'i 17.5 wanda ke ɗaukar kusan awanni 96 don sharewa gaba ɗaya daga jikin mutum. Idan aka kwatanta da kwaya mai launin shuɗi, Viagra, wanda ke da tasiri kawai na awanni 3 zuwa awanni 4 bayan cin abinci, Tadalafil ya fito a saman.
Babban aikin aikin miyagun ƙwayoyi yana hana enzyme PDE5 wanda ke cikin ƙwayoyin tsoka na jijiyoyin jini na azzakarin jini. Hana wannan enzyme yana haifar da vasodilation kuma a ƙarshe, ƙara yawan jini yana gudana ta cikin jijiyoyin jini, waɗanda ke kewaye da corpus cavernosa. Wannan tsokar azzakari, lokacin da aka sanya ta cikin damuwa ta hanyar karuwar jini, ana matsa shi zuwa madaidaicin wuri, wanda ake magana da shi azaman tsage.
Koyaya, tsokar azzakari, corpus cavernosa ya zama daidai, yana buƙatar hutawa da farko don tasoshin jini na iya fadadawa da karɓar babban shigar jini. Wannan annashuwa na tsokoki masu santsi shima sakamako ne na hana enzyme PDE5, kodayake a kaikaice. Hana PDE5 yana haifar da adadin Guanosine MonoPhosphate ko GMP, wanda ke da mahimmanci don shakatawa tsoffin tsokoki, kamar corpus cavernosa.
Koyaya, wannan ba shine kawai amfani da tsarin aikin Tadalafil Foda ba. Haka kuma ana amfani da magani na likitanci kawai don hyperplasia prostatic mara kyau, matsalar fitsarin da ya haifar da faɗaɗa ƙwayar prostate da gabatarwa azaman fitsari mai raɗaɗi. Injin aikin don maganin kumburin prostate mai girma shima ta hanyar karuwar matakan GMP a cikin ƙwayoyin tsoka masu santsi. Sakin waɗannan sel yana ba da damar wucewar fitsari cikin sauƙi kuma yana hana riƙe fitsari da zafi.
Hakanan an ba da umarnin Tadalafil Foda don hauhawar jini na huhu, kamar yadda tasirin hana PDE5 ba kawai yana ƙaruwa da hauhawar jini ba amma kuma yana rage hawan jini, wanda ke da fa'ida sosai a maganin PAH.
Menene Za a iya Amfani da Tadalafil Foda?
Ana amfani da Tadalafil Foda don maganin waɗannan yanayi:
- Erectile tabarbarewa
- Ƙwayar Ƙwayar Ƙwayoyin Ƙwaro
- Pulmonary Jijiya hauhawar jini
Kodayake ana gudanar da bincike kan sabbin hanyoyin amfani da maganin, a halin yanzu ana nufin kawai a ba shi umarnin maza sama da shekaru 18, waɗanda ke fama da ɗayan cututtukan da aka ambata a sama. Mafi yawanci, ana amfani da maganin don maganin tabarbarewa.
Amfanin Tadalafil Foda
Tadalafil yana da fa'idodi da yawa duka a kan kansa kuma idan aka kwatanta shi da sauran masu hana PDE5 waɗanda ke cikin rukunin magunguna masu motsa jima'i. Wannan maganin yana da ƙarfi kuma yana dindindin saboda yana ɗaukar awanni 36 kafin a share shi daga tsarin, kusan ba a iya gano shi bayan sa'o'i 96. Sakamakon maganin ya zama bayyananne kuma ana iya gani a kusa da mintuna 20 zuwa mintuna 60 bayan cin abinci, kuma foda Tadalafil yana ci gaba da aiki na kusan awanni 3 zuwa awanni 4 bayan haka. Yana da mahimmanci a ambaci cewa aikin miyagun ƙwayoyi ba ta kowace hanya yayi daidai da tsawon ginin.
Tadalafil Foda ba shi da ikon samar da kayan kwatsam kuma yana buƙatar motsawar jima'i da ta dace don ta kasance mai tasiri wajen samar da tsage. Idan an ba da kuzarin jima'i a cikin awanni huɗu da suka biyo bayan shan maganin, maganin na iya haifar da tsinke kuma ya sauƙaƙe alamun rashin ƙarfi.
This sex stimulant drug is quite effective in treating erectile dysfunction as a result of its prolonged mechanism of action, which makes it the drug of choice for many suffering from erectile dysfunction and benign prostatic hyperplasia. Tadalafil Powder may be combined with Tamulsin, another potent magani don magani of benign prostatic hyperplasia although the efficacy of this drug mixture is still being studied and analyzed.
Daidaitaccen Sashi na Tadalafil Foda
Tadalafil Foda, kamar yadda aka ambata a sama, galibi ana farawa da shi a 10 MG a matsayin mafi ƙarancin kashi mai yiwuwa. Bayan aƙalla mako guda na amfani da maganin, ƙila za a iya ragewa, ƙaruwa, ko kiyayewa a matakan daidai gwargwadon sakamakon. Duk da haka, yana da mahimmanci a tuna cewa wannan magani magani ne kawai-wanda yakamata ayi amfani dashi lokacin da ake buƙata. Hakanan yakamata ayi amfani dashi sau ɗaya kawai a cikin awanni 24 don kar a ƙara haɓaka tasirin maganin.
Rashin haɗarin kashi da aka rasa don magani wanda yakamata a ɗauka kawai lokacin da ake buƙata kusan babu shi duk da haka, yana da mahimmanci a fayyace jagororin don kashi da aka rasa. Wannan saboda an ba da umarnin maganin don amfanin yau da kullun, aƙalla sau uku a rana lokacin da ake amfani da shi don maganin hauhawar jini na huhu da hauhawar hauhawar jini. Idan akwai kashi da aka rasa, yana da kyau a guji wannan sashi gaba ɗaya, kuma babu wani yanayi da yakamata a rama kashi da aka rasa tare da kashi biyu a gaba. Wannan na iya haifar da sakamako mai tsawo sosai da wanda ba a so wanda ke da yuwuwar haifar da rikitarwa na kusan mutuwa.
Wanda Bai Kamata yayi Amfani da Tadalafil Foda ba
Tadalafil Powder has various benefits and uses but it is specifically designed for the male gender, especially those over the age of 18 years. The medication should not be taken by women and children as they may be at higher risk of developing several of the common illa and complications associated with Tadalafil Power use.
Jama'a masu zuwa kada su ɗauki Tadalafil Foda, ko tuntuɓi likitan su kafin fara duk wani magani na ƙungiyar masu hana hana PDE5:
- Mutanen da ke da tarihin aikin tiyata a cikin watanni uku da suka gabata
- Mutanen da ke da tarihin abubuwan da suka faru na zuciya a cikin watanni uku da suka gabata zuwa watanni shida
- Mutanen da ke fama da hauhawar jini da hyperlipidemia
- Mutanen da ke da cututtukan koda
- Mutane da retinitis pigmentosa
- Mutanen da ke da ciwon haemophilia ko rashin lafiya irin wannan
- Mutanen da ke da myeloma da yawa, ko cutar sankarar bargo
- Mutane masu ciwon ciki
- Mutanen da ke da tarihin bugun jini ko kuma tare da haɗarin haɗarin bugun jini
These people aren’t allowed to take Tadalafil because their current medications can interact with the drug, resulting in life-threatening complications. In some cases, these patients’ bodies may be more susceptible to the relatively common and non-serious illa of the drug but the intensity of complications may be higher than usual.
Hanyoyin da ke iya yiwuwa na Tadalafil Foda
Tadalafil Powder, like most medications, has several common illa associated with its use. However, none of them are serious, daily-life activities altering, or life-threatening. In fact, most of them will resolve on their own and will not require medical intervention.
Na kowa illa of Tadalafil include, but are not limited to:
- Dama hanci
- ciwon kai
- Dyspepsia
- Ciwon ciki
- Flushing; zafi da jajayen fata
- Tinnitus; m ringing ringing a cikin kunne
- Matsalar ji
- Binciken Blurry
- Rashin gani
- Priapism
Sakamakon sakamako na ƙarshe ya fi ƙanƙanta kuma yana nufin tsararraki mai raɗaɗi wanda ya daɗe, yawanci fiye da sa'o'i huɗu. A cikin irin waɗannan yanayi, ana ba da shawarar neman taimakon likita nan da nan saboda ya fi muni, ko da yake yana da wuya, illa na amfani da Tadalafil.
Tun daga watan Oktoba na 2007, FDA tana buƙatar duk kwantena na magunguna na PDE5 don haɗawa da alamar faɗakarwa wanda ke ba masu amfani damar sanin cewa waɗannan magunguna suna da yuwuwar haifar da asarar ji na ɗan lokaci. Wannan shawarar ta FDA ta kasance sakamakon korafe -korafe da yawa na asarar ji a cikin marasa lafiya da ke amfani da Tadalafil ko makamancin magungunan da aka yi wa rajista da FDA, suna buƙatar su bincika batun da kyau. Binciken FDA ya gano asarar ji yana da mummunan tasiri na TAdalafil wanda suka yi imanin yakamata a sanar da duk marasa lafiya, a bayyane, don haka zasu iya yanke shawara mai ma'ana.
Rashin hangen nesa har yanzu wani ƙaramin korafi ne da ke da alaƙa da amfani da Tadalafil kuma lokacin da FDA ta bincika waɗannan korafe-korafen, an gano cewa wannan sakamako mafi yawa yana faruwa ne a cikin marasa lafiya da ke fama da cututtukan ido, wato marasa arteritic antemic ischemic optic neuropathy ko NAION. Tun da babu wani dalili da sakamako na kai tsaye da FDA ta samu, babu alamar gargadi da ke da alaƙa da asarar hangen nesa a kan Tadalafil foda ko wasu masu hana jigilar PDE5.
Hulɗa da Magungunan Magunguna tare da Tadalafil Foda
Bai kamata a ɗauki wasu magunguna tare ba saboda za su iya hulɗa da kowane sakamakon da zai haifar da ko dai rage tasirin duka biyun, ƙara yawan tasirin duka biyun, ko haɓaka mummunan tasirin magungunan duka.
Tadalafil Foda shine irin wannan magani wanda bai kamata a ɗauka tare da magunguna masu zuwa ba.
- Antacids: Waɗannan magunguna suna hulɗa tare da Tadalafil don haka suna haifar da raguwar ingancin maganin na ƙarshe, kodayake har yanzu ba a fahimci ainihin injin ba. Koyaya, yana da mahimmanci a faɗakar da marasa lafiya game da yuwuwar hulɗa tsakanin waɗannan magunguna guda biyu, musamman kamar yadda tsohuwar ƙwayar magani ce gama gari.
- Masu hana PDE5: Amfani da magunguna tare da irin wannan tsarin aikin kamar Tadalafil na iya haifar da hauhawar hauhawar jini da raguwar barazanar rayuwa. Haɗa masu hana PDE5 daban -daban guda biyu ko ɗaukar kashi biyu na miyagun ƙwayoyi iri ɗaya na iya haifar da rikitarwa maimakon ƙarin fa'ida.
- Barasa: Shan foda Tadalafil tare da barasa ba zai iya haifar da wani takamaiman rikitarwa ba amma yana iya haifar da ƙaruwa mai yawa a cikin tsananin tasirin sakamako. Suna iya zama na kowa a faruwar amma idan aka tsananta, na iya zama ba za a iya jurewa ba kuma yana iya buƙatar taimakon likita.
- Nitrates: Ana amfani da waɗannan magunguna don dalilai na zuciya kuma babban aikin su shine ƙara yawan jini ta cikin jijiyoyin jini ta hanyar samun tasirin vasodilatory akan su. Wannan tsarin aikin yayi kama da na Tadalafil, saboda haka haɗuwar magungunan biyu yana haifar da ƙari daga mummunan tasirin magungunan duka.
- Anti Hypertensives: Dalilin hakan daidai yake da na nitrates. Anti hypertensives da Taladafil duk suna aiki akan rage hawan jini ta tasoshin jijiyoyin jini, wanda idan aka haɗa su, zai haifar da matsanancin hawan jini wanda zai iya haifar da mace -mace, idan ba a kula da shi ba.
- CYP3A4 Inducers: CYP3A4 shine enzyme da ke da alhakin fitar da fili na Tadalafil daga jiki bayan ya cika manufarsa. Koyaya, magani wanda ke haɓaka tasirin wannan enzyme zai haifar da ƙara fitar da Tadalafil, tun kafin ya sami damar cika manufarsa. Wannan ya sa ƙarshen baya da inganci kuma mara amfani.
- Masu hana CYP3A4: Duk wani magani da zai hana aikin CYP3A4 enzyme zai haifar da raguwar fitar da Tadalafil wanda zai bar shi a cikin tsarin ɗan adam fiye da yadda ya kamata. Wannan sakamako mai tsawo ba lallai bane kuma yana da yuwuwar zama mai haɗari gaba ɗaya, wanda shine dalilin da ya sa yakamata a guji haɗuwar waɗannan biyun ko ta halin kaka.
- Guanylate Cyclase Stimulators: Waɗannan magunguna suna yin niyya ga jijiyoyin huhu, da nufin rage matsin jinin da ke ratsa ta. Koyaya, wannan shima yana daga cikin fa'idodi masu fa'ida da amfani da Tadalafil. Haɗuwa da waɗannan biyun zai iya haifar da ƙarancin hawan jini na huhu, wanda zai iya zama mutuwa idan ba a dace ba kuma a bi da shi akan lokaci.
A ina ake sayar da Tadalafil Foda?
Tadalafil Powder manyan sana'o'in hannu sun fi yawa fiye da siyar da dillalai kamar yadda aka saba saya da yawa kai tsaye daga masana'antar kera Tadalafil Powder. Gabaɗaya, galibin magunguna na irin wannan yanayin masu zaman kansu ana siyan su akan layi saboda yana ba marasa lafiya hankali da sirrin da suke buƙata. Ana samun maganin a kusan dukkanin kantin magani na gida da na kan layi amma marasa lafiya suna buƙatar samun takardar izini don samun damar siyan ta.
Ƙarin Binciken Likitoci da Bayani
Tadalafil ana yin bincike akai akai kuma ana nazari don tantance duk wani yuwuwar amfani da maganin. Tadalafil shine mabuɗin mahaɗan a cikin magunguna daban -daban, duk ana siyar da su ƙarƙashin sunayen iri daban -daban, galibi don rikice -rikice kamar lalacewar erectile, benign prostatic hyperplasia, da hauhawar jini na huhu. Koyaya, akwai karatuttukan daban -daban waɗanda a cikin matakan su na farko sun nuna cewa Tadalafil, a nan gaba, ƙila za a iya ba da izini ga sauran cututtuka.
Ofaya daga cikin mahimman binciken da ake yi akan Tadalafil yana mai da hankali kan ingancin sa da amincin sa idan marasa lafiya da ke fama da matsalar tabarbarewa. An buga binciken a cikin Jaridar Lafiya ta Indonesiya, kuma dangane da binciken masu bincike na adabi daga rumbun adana bayanai na lantarki, ya kammala da cewa amfani da Tadalafil sau ɗaya a rana ya fi tasiri wajen magance tabarbarewa fiye da amfani da magani lokacin da ake buƙata.
Dalilin da yasa wannan binciken yake da mahimmanci shine cewa yana da yuwuwar canza ƙa'idodin jiyya don tabarbarewa. Koyaya, ana buƙatar ƙarin binciken kafin a sami canji a cikin tsare -tsaren magani.
Wani bincike a cikin Tadalafil yana da nufin sake dawo da magungunan kumburin jima'i, tare da miyagun ƙwayoyi na aji ɗaya, vardenafil, don amfani da su don magance cututtukan kashi. Rikicin kasusuwa anan yana nufin rikice-rikice inda osteoclast ko sel masu lalata kashi ke aiki cikin sauri kuma tare da ingantaccen aiki wanda bai dace da aikin osteoblast ko sel masu ƙashi ba. Wannan yana haifar da raguwar ƙashin kashi wanda ke sa marasa lafiya su kasance masu saurin kamuwa da karaya.
Lokacin binciken vivo na binciken ya nuna cewa duka waɗannan magungunan ba za su iya haɓaka ayyukan osteoblasts kawai ba amma a lokaci guda rage ayyukan osteoclasts. Magungunan suna iya yin wannan saboda hanyar PDE5A shine mabuɗin don samar da daidaiton nau'ikan sel guda biyu. Hanya ɗaya ita ce abin da magungunan ke nufi don maganin tabarbarewa. Bayan aikace -aikacen ra'ayoyin in vivo akan samfuran dabbobi ta masu binciken da ke jagorantar wannan binciken, an gano cewa duka magungunan biyu zaɓuɓɓuka ne masu dacewa don gudanar da ƙoshin lafiya mai ƙoshin lafiya. Duk da haka, ana buƙatar ci gaba da yin nazari kan tasirin magungunan duka biyun akan ƙashin mutane.
Nazarin meta-bincike da aka buga a Jaridar Endocrinology idan aka kwatanta ingancin maganin tadalafil, maganin tamsulosin, da tamsulosin da maganin tadalafil don taimakawa fitar da duwatsu urethral. Manufar binciken ita ce ba wai kawai samo sabbin hanyoyin haɗin gwiwa don taimakawa marasa lafiya da duwatsu ureteral ba har ma don tantance amincin waɗannan tsare -tsaren magani.
Amfani da tadalafil shi kaɗai ko tadalafil tare da tamsulosin sune zaɓuɓɓuka guda biyu waɗanda aka gano sune mafi inganci kuma mafi ƙarancin yiwuwar haifar da illa. Bugu da ƙari, tasirin analgesic na Tadalafil na iya samun damar rage raunin da yawancin marasa lafiya da duwatsu ureteral ke fuskanta yayin da magungunan ke taimakawa fitar da dutsen daga cikin tsarin.