Urolithin A 8-Methyl Ether

Afrilu 8, 2021

Urolithins sune metabolites na sakandare na ellagic acid waɗanda aka samo daga ellagitannins. A cikin mutane ellagitannins ana canza su ta hanyar gut microflora zuwa ellagic acid wanda aka kara canzawa zuwa urolithins A, urolithin B, urolithin C da urolithin D a cikin manyan hanji.

Urolithin A 8-Methyl Ether (35233-17-1) bidiyo

 

Urolithin A 8-Methyl Ether (35233-17-1)bayani dalla-dalla

Product Name Urolithin A 8-Methyl Ether foda
Chemical Name 3-hydroxy-8-methoxy-6H-benzo [c] chromen-6-daya;

3-hydroxy-8-methoxybenzo [c] chromen-6-daya;

35233-17-1;

MLS001049096;

SMR000386929;

ChemDiv3_002724;

Urolithin A 8-methyl Eter.

CAS Number 35233-17-1
InChIKey IGJLBTGXYKPECW-UHFFFAOYSA-N
kwayoyin FƘararraki C14H10O4
kwayoyin Wtakwas 242.23
Monoisotopic Mass 242.057909 g / mol
narkewa batu 242 ° C (Solv: acetic acid (64-19-7))
tafasar batu  479.9 ± 38.0 ° C (Tsinkaya)
Daminci 1.375 ± 0.06 g / cm3 (Tsinkaya)
Half Half-Life N / A
Launi Haske Beige zuwa Sosai Mai Haske Orange
Solubility  Acetone (Kaɗan, Sonicated) DMSO (lightananan, Sonicated), Methanol (lightananan)
Storage Taikin zafi  Hygroscopic, -20 ° C Freezer, A ƙarƙashin yanayin yanayi
Aaikace-aikace Urolithin A 8-Methyl Ether shine matsakaici a cikin kira na Urolithin A (U847000), babban abin da ke cikin Ellagitannin kuma yana nuna alamun kumburi da antioxidant.

 

reference

[1] Espín, Juan Carlos; Larrosa, Mar; García-Conesa, María Teresa; Tomás-Barberán, Francisco (2013). "Mahimmancin Halittu na Urolithins, Gut Microbial Ellagic Acid-Samu Metabolites: Shaida Har Yanzu". Arin Cikakken Bayani da Sauran Magunguna. 2013: 270418. doi: 1155/2013/270418. ISSN1741-427X. PMC 3679724. PMID 23781257.

[2] Ryu, Dongryeol; Mouchiroud, Laurent; Andreux, Pénélope A; Katsyuba, Elena; Moullan, Norman; Nicolet-dit-Félix, Amandine A; Williams, Evan G; Jha, Pooja; Sasso, Giuseppe Lo (2016). "Urolithin A yana haifar da mitophagy kuma yana tsawanta rayuwa a cikin C. elegans kuma yana ƙaruwa aikin tsoka a cikin beraye". Yanayi na Yanayi. 22 (8): 879–888. Doi: 1038 / nm.4132. PMID 27400265.

[3] Ishimoto, Hidekazu; Shibata, Mari; Myojin, Yuki; Ito, Hideyuki; Sugimoto, Yukio; Tai, Akihiro; Hatano, Tsutomu (2011). "In vivo anti-inflammatory da antioxidant Properties na ellagitannin metabolite urolithin A" (PDF). Haruffa na Bioorganic & Magungunan Chemistry. 21 (19): 5901-5904. Doi: 1016 / j.bmcl.2011.07.086. PMID 21843938.

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