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Raw Lorcaserin HCL foda (846589-98-8)

Raw Lorcaserin hydrochloride foda ne mai cike da karɓa mai karɓa na 2C (5-HT2C) da kuma maganin maganin maganin da ya dace ...


Status: A Mass Production
Naúra: 25kg / Drum
Capacity: 1380kg / watan

description

Raw Harshen HCL Mawasa (846589-98-8)

Raw Lorcaserin HCL foda (846589-98-8) Bayani

Product Name Raw Lorcaserin Hydrochloride foda
Chemical Name Raw Lorcaserin HCL foda, Lorcaserin
Brand Name BELVIQ
Drug Class 5-HT2C mai karɓar mai karɓa
CAS Number 846589-98-8
InChIKey ITIHHRMYZPNGRC-QRPNPIFTSA-N
kwayoyin FƘararraki C11H15Cl2N
kwayoyin Wtakwas 232.15
Monoisotopic Mass 231.058154899
Gyarawa Point Babu bayanai akwai
Freezing Point Babu bayanai akwai
Half Half-Life Rabin rabi na lorcaserin ne kamar 11 hours.Lorcaserin foda an kawar da farko a cikin fitsari (92%) da kuma a cikin feces (2.2%)
Launi White foda
solubility Rashin ruwa na ruwa: 0.0709 mg / ml
Storage Taikin zafi -20 ° C.
Aaikace-aikace Magunguna mai karɓa na srorotonin 2C (HT2C) don asarar nauyi.Da rage cin abinci da kuma inganta zaman lafiya a tsakiya

Raw Lorcaserin Hcl foda (846589-98-8) Bayani

Raw Lorcaserin hydrochloride foda ne mai samfurin hydrochloride da aka samo ta hanyar maganin lorcaserin foda tare da daya daidai da acid hydrochloric. An yi amfani da shi azaman ƙwayoyi masu guba. Lorcaserin hydrochloride na 5HT2c mai karɓar rashawa wanda aka nuna don amfani da manya da BMI ≥30, ko waɗanda suke tare da BMI ≥27 kuma akalla nau'in nau'in nau'i mai nauyi kamar hauhawar hawan jini, rubuta ciwon sukari 2 ko dyslipidemia.Lorcaserin Hydrochloride foda yana aiki ta wajen rage ci abinci yana haifar da jin dadi, kuma ana tsammanin ya kauce wa haɗuwa da cututtukan zuciya na valvular zuciya da ke haɗawa da kunnawa na masu karɓa na 5-HT2B, yankin kwakwalwa da aka sani ana taka muhimmiyar rawa wajen daidaita yanayin yunwa da cin abinci. Ta hanyar kunna wadannan masu karɓar ragawa, ƙwayar da ake samu a cikin ƙwayar salutattun ƙwayar gurbin ƙwayar katako mai iya rage yawan abinci ta hanyar rage yawan ci abinci da kuma sa mutum ya ji daɗi ko da bayan cin abinci marar abinci fiye da yadda ya saba. an amince da shi a yau ta hanyar FDA a cikin hukuncin yanke shawara bayan shekaru 2 na bincikar.

Ana ba da alamar samfurori mai gina jiki a cikin jiki mai saukin rage yawan karancin jiki (BMI na 30 kg / m2 ko mafi girma) kuma babba babba (BMI na 27 kg / m2 ko mafi girma) tare da akalla nau'in sharaɗɗa masu dangantaka da nauyi.

An yi amfani da man fetur na lantarki na Lorcaserin tare da abinci da motsa jiki don bi da kiba. Ana amfani da shi a wasu lokuta da kiba wanda zai iya dangantaka da ciwon sukari, high cholesterol, ko cutar hawan jini.

Lorcaserin hydrochloride ba za ta bi da wani yanayin lafiya ba (kamar cututtukan zuciya, ciwon sukari, hawan jini). Ci gaba da shan wasu magunguna da likitanku ya tsara don biyan waɗannan yanayi.

Hanyoyin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin Harkokin {asashen {asar Amirka

Kodayake ba'a san ainihin ainihin aikin ba, an yi imanin ya ƙunshi zaɓin zaɓi na masu karɓa na 5-HT2C a cikin ƙananan neorexigenic pro-opiomelanocortin ne a cikin tsakiya na hypothalamus. Wannan yana haifar da rage yawan abincin abinci da rashin jin daɗi ta hanyar inganta sakin hormone na alpha-melanocortin, wanda ke aiki akan masu karɓa na melanocortin-4.

Lorcaserin hydrochloride foda aiki ta hanyar sarrafawa ci - musamman ta hanyar kunna masu kwakwalwa kwakwalwa don serotonin, wani neurotransmitter cewa triggers ji na zaman lafiya da gamsuwa. Amfani da abinci yana sarrafawa ta cibiyar kula da kayan abinci, wanda yake cikin tsakiya mai kwakwalwa na hypothalamus da cibiyar abinci na yunwa da ke gabatar da hypothalamus a kaikaice. Sauran bayanai daga cibiyoyin da suka fi girma da ƙwayoyin gastrointestinal sun haɗa ne a tsakiya, inda wasu nau'i biyu masu amfani da kayan sarrafa abinci suke. Da fari dai, abincin abinci mai cin gashin abinci yana samar da gina jiki da ake kira neuropeptide Yuro; kuma na biyu, ƙungiyar cin zarafi ta abinci da ke dauke da cocaine da amphetamine da aka tsara lissafi (CART) da pro-opiomelanocortin (POMC). POMC ta ƙunshi masu karɓa na 5-HT 2C, wanda idan aka kunna sake fitar da hormone na alpha-melanocyte (alfa-MSH) .Yanyar haɓaka da ƙananan ƙwararraki sun ci gaba da ayyukan tsakiya na tsakiya a cikin hypothalamus. Cibiyar tazarar ta ƙunshi masu karɓa na 4 melanocyte (MC4R) wanda ke hana ci a cikin allurar rigakafi na lorcaserin hydrochloride foda yin aiki a matsayin magungunan 5-HT 2C a kan ƙananan POMC, wanda hakan ya sa aka saki alfa MSH. Ayyukan karin MSFA na aiki a kan MC4R a tsakiya ta tsakiya a cikin hypothalamus, wanda zai haifar da rage yawan ci. A cikin maganin supratherapeutic, lorcaserin hydrochlorider yana aiki a kan 5-HT 2B da kuma masu karɓa na 5-HT 2A.

amfanin na ƙwayar Lorcaserin Hcl (846589-98-8)

  • Lissafin Harkokin Cizon Cizon Casa ne mai amfani da agonist mai karɓar 5-HT2C wanda ake zaton zai rage yawan abincin abinci ta tsakiyar tsarin POMC. Lorcaserin HCL foda amfani:
  • Ana amfani da furotin na Cizon Lakaci tare da abinci da motsa jiki don bi da kiba.
  • Ana yin amfani da ƙwayar launi na LCCC a lokacin amfani da cutar da za a iya danganta da ciwon sukari, high cholesterol, ko cutar hawan jini.
  • Lissafin Cizon Labaran Casa ne ba za ta bi da wani yanayin lafiya ba (kamar cututtukan zuciya, ciwon sukari, hawan jini).

Shawarar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (846589-98-8) Dosage

Harshen Lincolin Harshen Cizon Labaran yana samuwa a cikin nau'i mai kwakwalwa kuma ana dauka yawanci 1-2 sau ɗaya a rana, tare da ko ba tare da abinci ba. Dole ne a yi amfani da laccoci din tare da rage yawan abincin calori da shirin motsa jiki.

Ƙwararren shawarar da aka yi a cikin ƙwayar katako na hcl shine 10 MG da aka yi ta bakin bakin sau biyu a rana. Za'a iya ɗaukar likita mai suna Lorcaserin ba tare da la'akari da abincin ba. Dole ne a dakatar da halayen Lincoln katallah a cikin marasa lafiyar da suka kasa cim ma asarar nauyin 5% a cikin makon 12 tun lokacin da waɗannan marasa lafiya ba su iya samun asarar nauyi mai mahimmanci tare da ci gaba da maganin ba.

Side effects na ƙwayar Lorcaserin Hcl (846589-98-8)

An yi amfani da ƙwayar katse mai suna Lorcaserin Hcl don maganin kulawa da kariya a cikin tsofaffi tare da nau'in nau'i na jiki (BMI) na 30 ko mafi girma (obese) a matsayin kari ga rage cin abinci mai rage yawan kalo da motsa jiki. Har ila yau, ana yarda dashi don amfani da tsofaffi da BMI na 27 ko mafi girma (ƙima) kuma waɗanda ke da akalla nauyin nauyin nau'i kamar jini da jini (hauhawar jini), ko high cholesterol (dyslipidemia). Duk da haka, shi ma yana da wasu tasiri. Kamar yadda a kasa:

Tshi ne sakamako mafi rinjaye:

  • -Bajada,
  • -Dizziness,
  • -Fatigue,
  • -Nausea,
  • -Da baki,
  • -Constipation, da kuma
  • -Hypoglycemia (ƙananan jini sugar).

Sauran ƙananan cututtukan da ke hade da lorcaserin sun hada da:

  • -Waɗanda ba a iya amfani da shi ba,
  • -Ya canzawa a hankali ko ƙwaƙwalwa,
  • -Munanan matsalolin,
  • -Depression ko tunani na kashe kansa,
  • -Faɗannan abubuwa,
  • -Ka sa zuciya,
  • -Dajin cikin ƙwayar jini, kuma
  • -An karuwa a cikin hormone, prolactin.

BATSA DA TATTAUNAWA:

Ana Samun Wannan Abubuwan ne Don Amfani da Bincike Kawai. Sharuɗɗan Siyarwa suna Aiwatarwa. Ba don Amfani da Dan Adam bane, ko Likita, dabbobi, ko Amfani na Gida.


Karin bayani & amsoshin samfurin

FDA ta amince da Lorcaserin HCL don maganin kiba

References

  1. Bohula, Erin A., Wiviott, Stephen D., McGuire, Darren K., Inzucchi, Silvio E., et al.: Tsaro na zuciya na zuciya na Lorcaserin a cikin Masarar Ƙari ko Obese, The New England Journal of Medicine, 2018
  2. Abinci da Drug Administration, Magunguna Target Tsarin Mulki Control, Online, Aka buga 17 Yuli 2012
  3. Ashley Gustafson, Cammile King, Jose AR, Cibiyar Nazarin Harkokin Kimiyyar Halitta ta Duniya, Litattafan PMC, MediMedia, Amurka Lorcaserin (Belviq), Online, Satumba 2013